Browsing by Author "Shariati, Laleh"
Now showing items 1-5 of 5
-
Association of clinical features with spike glycoprotein mutations in Iranian COVID-19 patients
Ahangarzadeh, Shahrzad; Yousefi, Alireza; Ranjbar, Mohammad Mehdi; Dabiri, Arezou; Zarepour, Atefeh; Sadeghi, Mahmoud; Heidari, Elham; Mazrui, Fariba; Hosseinzadeh, Majid; Ataei, Behrooz; Zarrabi, Ali; Shariati, Laleh; Javanmard, Shaghayegh Haghjooy (MDPI, 2022)Background: Mutations in spike glycoprotein, a critical protein of SARS-CoV-2, could directly impact pathogenicity and virulence. The D614G mutation, a non-synonymous mutation at position 614 of the spike glycoprotein, is ... -
Fluorescence anisotropy cytosensing of folate receptor positive tumor cells using 3D polyurethane-GO-foams modified with folic acid: molecular dynamics and in vitro studies
Esmaeili, Yasaman; Mohammadi, Zahra; Khavani, Mohammad; Sanati, Alireza; Shariati, Laleh; Seyedhosseini Ghaheh, Hooria; Bidram, Elham; Zarrabi, Ali (NLM (Medline), 2023)Integrated polyurethane (PU)-based foams modified with PEGylated graphene oxide and folic acid (PU@GO-PEG-FA) were developed with the goal of capturing and detecting tumor cells with precision. The detection of the modified ... -
Gene editing-based technologies for beta-hemoglobinopathies treatment
Rahimmanesh, Ilnaz; Boshtam, Maryam; Kouhpayeh, Shirin; Khanahmad, Hossein; Dabiri, Arezou; Ahangarzadeh, Shahrzad; Esmaeili, Yasaman; Bidram, Elham; Vaseghi, Golnaz; Haghjooy, Shaghayegh; Shariati, Laleh; Zarrabi, Ali; Varma, Rajender S. (MDPI, 2022)Simple Summary: β-thalassemia syndromes are clinically and genetically heterogeneous blood disorders presented by β-chain deficiency in hemoglobin production. Despite improvements in transfusion practices and chelation ... -
Graphene oxide quantum dot-chitosan nanotheranostic platform as a pH-responsive carrier for improving curcumin uptake internalization: In vitro & in silico study
Esmaeili, Yasaman; Seyedhosseini Ghaheh, Hooria; Ghasemi, Fahimeh; Shariati, Laleh; Rafienia, Mohammad; Bidram, Elham; Zarrabi, Ali (Elsevier, 2022)We herein fabricated a cancer nanotheranostics platform based on Graphene Oxide Quantum Dot-Chitosan-polyethylene glycol nanoconjugate (GOQD-CS-PEG), which were targeted with MUC-1 aptamer towards breast and colon tumors. ... -
The importance of SNPs at miRNA binding sites as biomarkers of gastric and colorectal cancers: a systematic review
Hajibabaie, Fatemeh; Abedpoor, Navid; Assareh, Nazanin; Tabatabaiefar, Mohammad Amin; Shariati, Laleh; Zarrabi, Ali (2022)Dysregulated mRNA-miRNA profiles might have the prospective to be used for early diagnosis of gastrointestinal cancers, estimating survival, and predicting response to treatment. Here, a novel biomarker based on miRNAs ...
