Browsing by Author "Sun Gungorurler, Eda"
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Can Wharton jelly derived or adipose tissue derived mesenchymal stem cell can be a treatment option for duchenne muscular dystrophy? answers as transcriptomic aspect
Sun Gungorurler, Eda; Karaoz, Erdal (2020)Introduction: Mesenchymal stem cells (MSCs) are able to differentiate into several cell lineages including skeletal muscle. In addition to their differentiation capacities, they have the ability to transfer their content ... -
Comparative analyses of immunosuppressive characteristics of bone-marrow, wharton's jelly, and adipose tissue-derived human mesenchymal stem cells
Karaöz, Erdal; Demircan, Pinar Cetinalp; Erman, Gulay; Sun Gungorurler, Eda; Sariboyaci, Ayla Eker (Galenos Yayincilik, 2017)Objective: Mesenchymal stem cells (MSCs), which possess immunosuppressive characteristics on induced T-cells, were shown to be applicable in prevention and treatment of graft-versus-host disease. However, knowledge of ... -
Comprehensive analysis of transcriptomic portrait of T-cell acute lymphoblastic leukemia by RNA sequencing
Sun Gungorurler, Eda; Ng, O. Hatirnaz; Erbilgin, Y.; Firtina, S.; Sayitoglu, M. (Pergamon-Elsevier Science Ltd, 2018)Objective: T cell-acute lymphoblastic leukemia (T-ALL) is one of the most aggressive treatment-resistant types of leukemia, which has no specific prognostic marker for disease follow up. Objective: The aim of this study ... -
Efficacy of stem cell therapy in ambulatory and nonambulatory children with Duchenne muscular dystrophy - Phase I-II
Dai, Alper; Baspinar, Osman; Yesilyurt, Ahmet; Sun Gungorurler, Eda; Aydemir, Cigdem Inci; Oztel, Olga Nehir; Karaoz, Erdal (Dove Medical Press Ltd, 2018)Purpose: Duchenne muscular dystrophy (DMD) is an X-linked recessive pediatric disorder that ultimately leads to progressive muscle degeneration. It has been known that cell-based therapies were used to promote muscle ... -
Genomic and proteomic monitoring of stem cell-derived exosomes
Karaoz, Erdal; Sun Gungorurler, Eda (HUMANA PRESS INC, 2019)The mesenchymal stem cell (MSC) transplantations are increasing day by day in clinical therapies. Recent studies have described that the treatment activities of MSCs are mediated by paracrine factors secreted. These paracrine ... -
Lösemi modelinde tüm Genom RNA dizileme analiz algoritması geliştirilmesi
Sun Gungorurler, Eda; Sayitoglu, Muge (DergiPark, 2020)Amaç: RNA Dizileme teknolojisi gen anlatım farklılıkları ve kodlayan bölgedeki varyasyonlar, kodlama yapmayan küçük RNAların anlatımları ve gen füzyonlarının belirlenmesi ile bu farklılıkların nedenlerini sunabilmektedir. ... -
Mesenchymal stem cell-derived exosomes do not promote the proliferation of cancer cells in vitro
Nowadays, the use of Mesenchymal stem cells (MSCs) in clinical therapies have an increased acceleration, while it constitutes two sides of yin-yang with its ameliorating effects in regenerative medicine and promoting effects ... -
Safety and efficacy of the stem cell transplantation in friedreich's ataxia: a report of three cases
Azeri, Riza; Irmak, Duygu Koyuncu; Sun, Eda; Karaoz, Erdal (IJPHY PUBLISHERS, 2021)Background: Friedreich's ataxia is a progressive degenerative disorder caused by deficiency of the frataxin protein. Expanded GAA repeats in intron 1 of the FXN gene lead to its heterochromatinization and transcriptional ...
