Browsing by Author "Tezcan Karasu, Gulsun"
Now showing items 1-8 of 8
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Genomic spectrum and phenotypic heterogeneity of human IL-21 receptor deficiency
Cagdas, Deniz; Baris, Safa; Worley, Lisa; Langley, David B.; Metin, Ayse; Karasu, Gulsun (Springer, 2021)Biallelic inactivating mutations in IL21R causes a combined immunodeficiency that is often complicated by cryptosporidium infections. While eight IL-21R-deficient patients have been reported previously, the natural course, ... -
Hematopoetic stem cell transplantation in CD40 ligand deficiency
Uygun, Vedat; Uygun, Dilara Fatma Kocacik; Daloglu, Hayriye; Ozturkmen, Seda; Kilic, Suar Caki; Bingol, Aysen; Yalcin, Koray; Celen, Safiye Suna; Hazar, Volkan; Tezcan Karasu, Gulsun; Yesilipek, Akif (SPRINGERNATURE, 2020)[No Abstract] -
Hematopoietic stem cell transplantation in CD40 ligand deficiency: a single-center experience
Uygun, Dilara Fatma Kocacik; Uygun, Vedat; Tezcan Karasu, Gulsun; Daloglu, Hayriye; Ozturkmen, Seda Irmak; Celmeli, Fatih; Torun, Selda Hancerli; Ozen, Ahmet; Baris, Safa; Aydiner, Elif Karakoc; Yalcin, Koray; Kilic, Suar Caki; Hazar, Volkan; Bingol, Aysen; Yesilipek, Akif (Wiley, 2020)Deficiency of the CD40L, expressed on the surface of T lymphocytes, is caused by mutations in the glycoproteinCD40L (CD154)gene. Resulting defective humoral and cellular responses cause a clinical presentation that includes ... -
ILC3 deficiency and generalized ILC abnormalities in DOCK8-deficient patients
Eken, Ahmet; Cansever, Murat; Okus, Fatma Zehra; Erdem, Serife; Nain, Ercan; Azizoglu, Zehra Busra; Haliloglu, Yesim; Karakukcu, Musa; Ozcan, Alper; Devecioglu, Omer; Aksu, Guzide; Arikan Ayyildiz, Zeynep; Topal, Erdem; Karakoc Aydiner, Elif; Kiykim, Ayca; Metin, Ayse; Erol Cipe, Funda; Kaya, Aysenur; Artac, Hasibe; Reisli, Ismail; Guner, Sukru N.; Uygun, Vedat; Tezcan Karasu, Gulsun; Doenmez Altuntas, Hamiyet; Canatan, Halit; Oukka, Mohamed; Ozen, Ahmet; Chatila, Talal A.; Keles, Sevgi; Baris, Safa; Unal, Ekrem; Patiroglu, Turkan (Wiley, 2020)BackgroundDedicator of cytokinesis 8 (DOCK8) deficiency is the main cause of the autosomal recessive hyper-IgE syndrome (HIES). We previously reported the selective loss of group 3 innate lymphoid cell (ILC) number and ... -
Pearson syndrome in a patient transplanted for diamond-blackfan anemia
Tezcan Karasu, Gulsun; Uygun, Vedat; Daloglu, Hayriye; Ozturkmen, Seda; Yesilipek, Akif (SPRINGERNATURE, 2020)[No Abstract] -
Prognostic factors for survival in children who relapsed after allogeneic hematopoietic stem cell transplantation for acute leukemia
Hazar, Volkan; Tezcan Karasu, Gulsun; Ozturk, Gulyuz; Kupesiz, Alphan; Aksoylar, Serap; Ozbek, Namık; Uygun, Vedat; Ileri, Talia; Okur, Fatma Visal; Kocak, Ulker; Caki Kilic, Suar; Akcay, Arzu; Guler, Elif; Kansoy, Savas; Karakukcu, Musa; Bayram, Ibrahim; Aksu , Tekin; Yesilipek, Akif; Karagun, Barbaros Sahin; Yilmaz, Sebnem; Ertem, Mehmet; Uckan, Duygu; Fisgin, Tunc; Gursel, Orhan; Yaman, Yöntem; Bozkurt, Ceyhun; Gokce, Muge (2020)Background: Post-transplant relapse has a dismal prognosis in children with acute leukemia undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT). Data on risk factors, treatment options, and outcomes ... -
Ruxolitinib salvage therapy is effective for steroid-refractory graft-versus-host disease in children: a single-center experience
Uygun, Vedat; Tezcan Karasu, Gulsun; Daloglu, Hayriye; Ozturkmen, Seda; Kilic, Suar Caki; Yalcin, Koray; Celen, Safiye Suna; Hazar, Volkan; Yesilipek, Akif (Wiley, 2020)Background Despite the increasing performance of allogeneic hematopoietic cell transplantation over the last decades, graft-versus-host disease (GVHD) remains the main cause of morbidity and mortality. The efficacy of ... -
Use of low cell dose for unmanipulated donor lymphocyte for management of cytomegalovirus infection: a single-center experience
Uygun, Vedat; Tezcan Karasu, Gulsun; Daloglu, Hayriye; Ozturkmen, Seda; Yalcın, Koray; Celen, Safiye Suna; Yesilipek, Akif (2020)Although advancements have been made in monitoring and preventing viral infections in HSCT patients, CMV reactivation still remains a critical post-transplant complication. Adoptive cell therapy is an alternative to ...
