Browsing by Author "Yang, Xiuli"

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Antibodies against EGF-like domains in Ixodes scapularis BM86 orthologs impact tick feeding and survival of Borrelia burgdorferi

Koči, Juraj; Bista, Sandhya; Chirania, Payal; Yang, Xiuli; Kitsou, Chrysoula; Buyuktanir Yas, Ozlem (Nature Publishing Group, 2021)

Ixodes scapularis ticks transmit multiple pathogens, including Borrelia burgdorferi sensu stricto, and encode many proteins harboring epidermal growth factor (EGF)-like domains. We show that I. scapularis produces multiple ...
A novel tick protein supports integrity of gut peritrophic matrix impacting existence of gut microbiome and Lyme disease pathogens

Yang, Xiuli; Koci, Juraj; Smith, Alexis A; Zhuang, Xuran; Sharma, Kavita; Dutta, Shraboni; Rana, Vipin Singh; Kitsou, Chrysoula; Buyuktanir Yas, Ozlem; Mongodin, Emmanuel F; Pal, Utpal (2021)

The peritrophic matrix (PM) is an acellular membrane that covers the gut epithelium in arthropods and physically separates it from the lumen. The structure is thought to play an important role in tick biology. The PM is ...