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Curcumin and its derivatives in cancer therapy: potentiating antitumor activity of cisplatin and reducing side effects
(WILEY, 2021)
Curcumin is a phytochemical isolated from Curcuma longa with potent tumor-suppressor activity, which has shown significant efficacy in pre-clinical and clinical studies. Curcumin stimulates cell death, triggers cycle arrest, ...
Cervical cancer progression is regulated by SOX transcription factors: Revealing signaling networks and therapeutic strategies
(Elsevier Science, 2021)
Cervical cancer is the fourth common gynecologic cancer and is considered as second leading cause of death among women. Various strategies are applied in treatment of cervical cancer including radiotherapy, chemotherapy ...
Editing SOX genes by CRISPR-Cas: current insights and future perspectives
(MDPI, 2021)
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and its associated proteins (Cas) is an adaptive immune system in archaea and most bacteria. By repurposing these systems for use in eukaryote cells, a ...
Mesoporous bioactive glasses in cancer diagnosis and therapy: stimuli-responsive, toxicity, immunogenicity, and clinical translation
(Wiley, 2021)
Cancer is one of the top life-threatening dangers to the human survival, accounting for over 10 million deaths per year. Bioactive glasses have developed dramatically since their discovery 50 years ago, with applications ...
Photodynamic therapy for leishmaniasis: recent advances and future trends
(Elsevier Science, 2021)
Leishmaniasis has infected more than 12 million people worldwide. The neglected tropical disease causing 20,000-30,000 deaths per year determined as a global health problem. The emergence of resistant parasites and serious ...
Intuitionistic fuzzy set of Γ-submodules and its application in modeling spread of viral diseases, mutated COVID-n, via flights
(John Wiley and Sons Ltd, 2021)
In this study, we generalize fuzzy (Formula presented.) -module, as intuitionistic fuzzy (Formula presented.) -submodule of (Formula presented.) -module (IF (Formula presented.) M), and utilize it for modeling the spread ...
Lycopene: food sources, biological activities, and human health benefits
(Hindawi, 2021)
As an antioxidant, lycopene has acquired importance as it prevents autoxidation of fats and related products. Tomatoes are an important agricultural product that is a great source of lycopene. It contains many vitamins and ...
Wnt/β-Catenin signaling as a driver of hepatocellular carcinoma progression: an emphasis on molecular pathways
(Dove Medical Press, 2021)
Liver cancers cause a high rate of death worldwide and hepatocellular carcinoma (HCC) is considered as the most common primary liver cancer. HCC remains a challenging disease to treat. Wnt/β-catenin signaling pathway is ...
Chitosan: a versatile bio-platform for breast cancer theranostics
(ELSEVIER, 2022)
Breast cancer is considered one of the utmost neoplastic diseases globally, with a high death rate of patients. Over the last decades, many approaches have been studied to early diagnose and treat it, such as chemotherapy, ...
Transition Metal Dichalcogenides (TMDC)-Based Nanozymes for Biosensing and Therapeutic Applications
(MDPI, 2022)
Nanozymes, a type of nanomaterial with enzyme-like properties, are a promising alternative to natural enzymes. In particular, transition metal dichalcogenides (TMDCs, with the general formula MX2, where M represents a ...