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Naftakinon türevli yeni sentez bileşiklerin kanser hücre hatları üzerine etkisinin incelenmesi
(İstinye Üniversitesi / Sağlık Bilimleri Enstitüsü, 2020)
Prostat kanseri dünyada ikinci, İskandinavya da dahil gelişmiş ülkelerde ise en sık rastlanan birinci kanser türüdür. Hormon ve/veya kemoterapi tedavisi sonrası hücrelerde meydana gelen direnç kanser kaynaklı ölümlerin ...
Etoposide loaded SPION-PNIPAM nanoparticles improve the in vitro therapeutic outcome on metastatic prostate cancer cells via enhanced apoptosis
Prostate cancer is among the leading causes of death worldwide because its metastatic form is a deadly disease. Therefore, the development of new chemotherapeutics is of immense importance. Nanoparticle technology seems ...
Unfolded Protein Response is Involved in Trans-Platinum (II) Complex-Induced Apoptosis in Prostate Cancer Cells via ROS Accumulation
(Bentham Science Publ Ltd, 2019)
Background: Prostate cancer is one of the most common cancer types and it is the sixth leading cause of cancer-related death in men worldwide. Even though novel treatment modalities have been developed, it still a ...
Mechanisms of abemaciclib, a CDK4/6 inhibitor, induced apoptotic cell death in prostate cancer cells in vitro
The therapeutic effects of abemaciclib (ABE), an inhibitor of cyclin- dependent kinases (CDK) 4/6, on the proliferation of two types of prostate cancer (PC) cells were revealed. In this study, in vitro cytotoxic and apoptotic ...