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The use of allogeneic mesenchymal stem cells in childhood steroid-resistant acute graft-versus-host disease: a retrospective study of a single-center experience
(Galenos Yayincilik, 2019)
Objective: Steroid-resistant acute graft-versus-host disease (srAGVHD) is the most important cause of morbidity and mortality after allogeneic stem cell transplantation. There are several treatment methods available, ...
Assessment of serum vitamin D in pediatric hematopoietic stem cell transplantation patients and its relation with complications
(Nature Publishing Group, 2018)
Recently, evaluation of serum vitamin D
level in pediatric hematopoietic stem cell transplantation
(HSCT) patients gained popularity, as there is close relation
with development of GVHD and complications. Our aim
was ...
Beta globin mutations in Turkish, northern Iraqi and albanian patients with beta thalassemia major
(Pagepress Publ, 2018)
The mutation detection of beta thalassemia is absolutely necessary for molecular diagnosis, as well as any genetic epidemiological study. The b globin gene has 3 exons and 2 introns, involved in beta-thalassemic pathogenesis. ...
Comparison of turkish stem cell coordination center (TURKOK) with Istanbul university bone marrow bank (TRIS); A single center experience in match unrelated donors
(Nature Publishing Group, 2019)
Match family donors are the preferable
options in allogenic stem cell transplant. However, in the
absence of donor relatives match unrelated donors have
been an option. In this study, the donor screening, transplant
...
Comparison of allogeneic stem cell transplantation results from related or unrelated donors in beta-thalassemia major
(Nature Publishing Group, 2019)
Although there have been significant
improvements with conventional therapies in beta thalassemia
major, hematopoietic stem cell transplantation is
only curative therapy. Related donors are preferred to
diminish ...
Extracorporeal photopheresis treatment for steroid resistant graft versus host disease in pediatrics: single center experience
(Nature Publishing Group, 2019)
Background: Steroid resistant graft vs host disease (GVHD) is defined as unresolved or worsened symptomatology of GVHD at day 14 despite effective immunosuppression with steroid therapy. Second line immunosuppressive agents, ...
Hit three birds with one stone: successful stem cell transplantation from one family donor to three siblings
(Nature Publishing Group, 2019)
Background: Thalassemia major is a single gene related hereditary hemoglobinopaty required life long regular transfusions with chelation therapies. Stem cell transplantation is the only curative treatment of the disease. ...
Donor lymphocyte infusion administrations after allogeneic stem cell transplantations in pediatrics: a single center experience
(Nature Publishing Group, 2019)
Loss of chimerism is one of the major problems
after allogeneic stem cell transplantation(SCT).
Donor- lymphocyte infusions(DLI) are used as a treatment
after taper or stopping immunosuppression. In this study,
DLI ...
Primary immunodeficiencies: HSCT experiences of a single center in Turkey
(WILEY, 2021)
Background Primary immunodeficiency diseases (PID) are characterized by the occurrence of frequent infections and are caused by many genetic defects. Hematopoietic stem cell transplantation (HSCT) is the only curative ...
Biallelic form of a known CD3E mutation in a patient with severe combined immunodeficiency
(Springer/Plenum Publishers, 2020)
T cell receptor (TCR) complex consists of αβ or γδ TCR
chains in combination with four CD3 subunits, CD3ε, CD3γ,
CD3δ, and CDζ [1]. This complex is required for thymocyte
development and the initiation of T cell-mediated ...
