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Phase I study on the safety and preliminary efficacy of allogeneic mesenchymal stem cells in hypoxic-ischemic encephalopathy
(Baishideng Publishing Group Co, 2021)
BACKGROUND Hypoxic-ischemic encephalopathy (HIE) is a leading cause of morbidity and mortality in the adult as well as in the neonate, with limited options for treatment and significant dysfunctionality. AIM To investigate ...
Functional recovery after wharton’s jelly–derived mesenchymal stem cell administration in a patient with traumatic spinal cord injury: a pilot study
(Gelenos, 2021)
The use of stem cells in the treatment of traumatic spinal cord injury (SCI) in recent years has provided promising results. Different sources
of cells for transplantation have been used, including mesenchymal stem cells ...
Feasibility of allogeneic mesenchymal stem cells in pediatric hypoxic-ischemic encephalopathy: phase I study
(Baishideng Publishing Group Co, 2021)
Background Hypoxic-ischemic encephalopathy (HIE) is one of the leading causes of death and long-term neurological impairment in the pediatric population. Despite a limited number of treatments to cure HIE, stem cell therapies ...
Effects of VEGF plus adipose tissue derived mesenchymal stem cells with platelet rich plasma on inbred rat ovarian functions in premature ovarian insufficiency model
(Oxford Univ Press, 2017)
What is known already: Numerous studies have found an increased risk of congenital malformations among live-born children conceived after assisted reproduction compared with spontaneously conceivedchildren. The underlying ...
Age-related changes in the immunomodulatory effects of human dental pulp derived mesenchymal stem cells on the CD4 + T cell subsets
(2021)
Mesenchymal stem cells (MSCs) are powerful immunomodulatory cells. The effects of the aging on these abilities of MSCs have not been adequately clarified. In this study, alterations in immunomodulatory abilities of MSCs ...
Histopathological, immunohistochemical, and biomechanical effects of splenectomy on Achilles tendon healing in rats
(Taylor & Francis Inc, 2019)
Purpose: This study aimed to assess Achilles tendon repair in rats following splenectomy to simulate patients with musculoskeletal system injury who had splenectomy after spleen injury, a situation often seen in orthopedics ...
Glioblastoma stem cells and comparison of isolation methods
(2019)
Background: Glioblastoma (GBM) is the most aggressive and the most common primary brain tumor. Over the last few years, studies have identified many genetical and phenotypical molecular situations for developing new treatment ...
Olfactory ensheathing cells: unique glial cells promising for treatments of spinal cord injury
(Wiley, 2021)
Spinal cord injury (SCI) is generally the consequence of physical damage, which may result in devastating consequences such as paraplegia or paralysis. Some certain candidates for SCI repair are olfactory ensheathing cells ...
SDF-1 modulates periodontal ligament-Mesenchymal Stem Cells (pdl-MSCs)
(WILEY, 2021)
Background/objectives: In this in vitro study, the effects of Stromal cell-derived factor-1 (SDF-1) was evaluated on the periodontal ligament-Mesenchymal Stem Cells (pdl-MSCs) functions.
Material and methods: Real-time ...
Mesenchymal stem cells increase antioxidant capacity in intestinal ischemia/reperfusion damage
(W B Saunders Co-Elsevier Inc, 2017)
Background: Mesenchymal stemcells (MSCs) may have beneficial effects in reversing intestinal damage resulting fromcirculatory disorders. The hypothesis of this study is thatMSCs increase antioxidant capacity of small bowel ...
