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Nonapoptotic cell death induced by Hypericum species on cancer cells
(2017)
Objectives. There are approximately 400 Hypericum species that grow naturally in different geographic originsof the world. Those species have been used in different folk medicines and screened for their biological ...
Kalsitriol ve doksorubisin kombinasyonunun MCF7 üzerine olası anti kanser etkilerinin araştırılması
(DergiPark, 2018)
Amaç: Bu çalışmada amacımız, belirli bir dozun üzerinde kardiyak yan etkileri oldukça fazla olan ve meme kanseri tedavisinde kullanılan kemoterapötiklerden doksorubisinin, tedavide kullanım miktarlarını azaltmayı ve ...
Prognostic biomarkers in lung cancer patients in terms of long-term survival
(DergiPark, 2021)
Introduction: We aimed to investigate the predictive effect of serum M30 and M65 antigens on long-term prognosis in patients with advanced stage lung cancer before and after the first dose of chemotherapy. Methods: Fourty ...
Water-soluble silver(I) complexes with N-donor benzimidazole ligands containing an imidazolium core: stability and preliminary biological studies
(Royal Society of Chemistry, 2021)
Herein, we report the synthesis, characterisation and preliminary biological evaluation of two novel silver(I) complexes of type [AgL2](NO3)3 (3 and 4) with ionic N-donor benzimidazoles. The complexes have been synthesized ...
Structural studies and cytotoxic activity of a new dinuclear coordination compound of palladium(II)-2,2:6,2-terpyridine with rigid dianionic 1,2,4-triazole-3-sulfonate linker
(Wiley, 2018)
A new dinuclear coordination compound of palladium(II), [Pd-2(terpy)(2)(-tas-N-1,N-4)]SO(4)11H(2)O (1), was synthesized by tethering a doubly deprotonated 1,2,4-triazole-3-sulfonate (tas) linker generated in situ via ...
A novel 1,4-naphthoquinone-derived compound induces apoptotic cell death in breast cancer cells
(Tubitak Scientific & Technical Research Council Turkey, 2019)
Breast cancer is the most-diagnosed cancer type among women. The triple-negative subtype is an especially aggressive type of breast cancer. Although chemotherapy is almost the only option for the treatment of triple-negative ...
A promising natural product, pristimerin, results in cytotoxicity against breast cancer stem cells in vitro and xenografts in vivo through apoptosis and an incomplete autopaghy in breast cancer
(Academic Press Ltd- Elsevier Science Ltd, 2018)
Several natural products have been suggested as effective agents for the treatment of cancer. Given the important role of CSCs (Cancer Stem Cells) in cancer, which is a trendy hypothesis, it is worth investigating the ...
Toxicity assessment of Hypericum olympicum subsp. olympicum L. on human lymphocytes and breast cancer cell lines
(Univ South Bohemia, 2020)
There is a limited number of studies about the constituents of Hypericum olympicum subsp. olympicum and its genotoxic and cytotoxic potency. We examined the possible antigenotoxic/genotoxic properties of methanolic extract ...
Effects of novel targeted anticancer drugs on cytotoxicity, apoptosis, angiogenesis, EMT, drug resistance and autophagic mechanism
(Oxford Univ Press, 2019)
Background: Metastatic coloncancer has asurvival rate less than %5 despite the use of effective chemotherapeutic regimen. Prognosticand predictiveimportance of EGFR is still contradictivein coloncancer. Tyrosine kinase ...
