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Biallelic form of a known CD3E mutation in a patient with severe combined immunodeficiency

Erman, Baran; Firtina, Sinem; Fisgin, Tunc; Bozkurt, Ceyhun; Erol Cipe, Funda (Springer/Plenum Publishers, 2020)

T cell receptor (TCR) complex consists of αβ or γδ TCR chains in combination with four CD3 subunits, CD3ε, CD3γ, CD3δ, and CDζ [1]. This complex is required for thymocyte development and the initiation of T cell-mediated ...

Are the anxiety levels of pediatric hematology-oncology patients different from healthy peers during the COVID-19 outbreak?

Cakiroglu, Suleyman; Yeltekin, Ceren; Fisgin, Tunc; Oner, Ozlem B; Adakli Aksoy, Basak; Bozkurt, Ceyhun (2020)

The COVID-19 outbreak has caused anxiety among children with hematology-oncology disease and their families, as it has in every segment of society. In this study, we aimed to detect the anxiety levels of children with ...

Invasive saprochaete capitata Infection in a patient with autosomal recessive CARD9 deficiency and a review of the literature

Erman, Baran; Firtina, Sinem; Aksoy, Basak Adakli; Aydogdu, Selime; Genc, Gonca Erkose; Dogan, Oner; Bozkurt, Ceyhun; Fisgin, Tunc; Erol Cipe, Funda (Springer/Plenum Publishers, 2020)

Purpose Autosomal recessive (AR) CARD9 deficiency is an inherited immune disorder which results in impaired innate immunity against various fungi. Superficial and invasive fungal infections, mainly caused by Candida or ...

Prognostic factors for survival in children who relapsed after allogeneic hematopoietic stem cell transplantation for acute leukemia

Hazar, Volkan; Tezcan Karasu, Gulsun; Ozturk, Gulyuz; Kupesiz, Alphan; Aksoylar, Serap; Ozbek, Namık; Uygun, Vedat; Ileri, Talia; Okur, Fatma Visal; Kocak, Ulker; Caki Kilic, Suar; Akcay, Arzu; Guler, Elif; Kansoy, Savas; Karakukcu, Musa; Bayram, Ibrahim; Aksu , Tekin; Yesilipek, Akif; Karagun, Barbaros Sahin; Yilmaz, Sebnem; Ertem, Mehmet; Uckan, Duygu; Fisgin, Tunc; Gursel, Orhan; Yaman, Yöntem; Bozkurt, Ceyhun; Gokce, Muge (2020)

Background: Post-transplant relapse has a dismal prognosis in children with acute leukemia undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT). Data on risk factors, treatment options, and outcomes ...

CMV-specific T-Cells for Treatment of CMV infection after hematopoietic stem cell transplantation in a pediatric case: First application in Turkey

Celilova, Sevil; Toret, Ersin; Adakli Aksoy, Basak; Ovali, Ercument; Bozkurt, Ceyhun (Galenos Yayincilik, 2020)

Cytomegalovirus (CMV) infection is still a major complication after allogeneic hematopoietic stem cell transplantation (HSCT) [1,2]. Unfortunately, prolonged antiviral treatment of CMV infection causes a delayed ...

Cross-sectional study: long term follow-up care for pediatric cancer survivors in a developing country, Turkey: current status, challenges, and future perspectives

Incesoy Ozdemir, Sonay; Tacyildiz, Nurdan; Varan, Ali; Kebudi, Rejin; Zulfikar, Osman Bülent; Celkan, Tulin Tiraje; Sahin, Gurses; Corapcioglu, Funda Vesile; Keskin Yildirim, Zuhal; Pinarli, Faruk Guclu; Olgun, Hatice Nur; Sari, Neriman; Dagdemir, Ayhan; Ozyoruk, Derya; Eren, Tuba; Cakir, Fatma Betul; Adakli Aksoy, Basak; Bozkurt, Ceyhun; Guler, Elif; Ozguven, Ali Aykan; Erbey, Mehmet Fatih; Berber Hamamci, Melda; Dincaslan, Handan; Unal, Emel; Kantar, Mehmet (Scientific and Technical Research Council of Turkey, 2020)

Aim: The main purpose of this study is to determine the current status of long-term follow-up (LTFU) for childhood cancer survivors and the challenges of LTFU for pediatric cancer survivors at pediatric oncology institutions ...