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Identification of microenvironmental regulation and therapeutic targeting of oncogenic eEF2K in pancreatic cancer
Eukaryotic elongation factor 2 kinase (eEF2K) is overexpressed in cancer cells and its overexpression is correlated with poor prognosis in several types of cancer. It has been known that pancreatic cancer (PaCa) has a ...
Identification of microenvironmental regulation and therapeutic targeting of ongenic EF-2 kinase in pancreatic cancer
(Science Direct, 2018)
Introduction Pancreatic cancer (PaCa) is one of the most aggressive and deadliest cancer with 6 months average survival rate. Recent studies indicate that the tumour microenvironment (TME) plays an important role in all ...