Now showing items 1-6 of 6
The effect of performance score, prognostic nutritional index, serum neutrophil-to-lymphocyte ratio, and thrombocyte-to-lymphocyte ratio on prognosis in non-small cell lung cancer
(MARMARA UNIV, 2022)
Objective: Systemic inflammatory markers and nutritional status of the patients can be helpful both in identifying high-risk cancer patients and in showing the prognosis of the disease. In this study we aimed to determine ...
H460 küçük hücreli dışı akciğer kanseri hücrelerinden kanser kök hücre izolasyonu ve karakterizasyonu
(İstinye Üniversitesi / Sağlık Bilimleri Enstitüsü / Tıbbi Biyoloji ve Genetik Ana Bilim Dalı, 2022)
Cancer is a disease of mutated and uncontrollably cells that can occur anywhere in human body. Lung cancer is one of the most common cancer and the leading cause of death in the world and our country. According to the ...
Radiotherapy-induced cardiotoxicity after the treatment of pulmonary and mediastinal solid tumors
(Istanbul Tip Fakultesi, 2022)
Thoracic tumors are extremely common and radiotherapy plays an important role in the treatment of these malignancies. Cardiac radiation exposure which is inevitable during thoracic radiotherapy may damage the heart muscle, ...
Long non-coding RNAs and exosomal incRNAs: Potential functions in lung cancer progression, drug resistance and tumor microenvironment remodeling
(Elsevier Science, 2022)
Among the different kinds of tumors threatening human life, lung cancer is one that is commonly observed in both males and females. The aggressive behavior of lung cancer and interactions occurring in tumor microenvironment ...
Applying quality by design approach for the determination of potent paclitaxel loaded poly(lactic acid) based implants for localized tumor drug delivery
(Taylor and Francis, 2022)
In the present study, poly(lactic acid) (PLA) and poly(ethylene succinate) (PESu) or poly(ethylene glycol) (PEG) under the framework of quality by design, were blended to produce effective sustained-release matrices for ...
Pyruvate dehydrogenase contributes to drug resistance of lung cancer cells through epithelial mesenchymal transition
(Frontiers Media S.A., 2022)
Recently, there has been a growing interest on the role of mitochondria in metastatic cascade. Several reports have shown the preferential utilization of glycolytic pathway instead of mitochondrial respiration for energy ...