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Transforming growth factor-beta (TGF-β) in prostate cancer: A dual function mediator?

Mirzaei, S.; Paskeh, M.D.A.; Saghari, Y.; Zarrabi, A.; Hamblin, M.R.; Entezari, M.; Hashemi, M.; Aref, A.R.; Hushmandi, K.; Kumar, A.P.; Rabiee, N.; Ashrafizadeh, M. (Elsevier B.V., 2022)

Transforming growth factor-beta (TGF-β) is a member of a family of secreted cytokines with vital biological functions in cells. The abnormal expression of TGF-β signaling is a common finding in pathological conditions, ...

Response to first‑line chemotherapy regimen is associated with efficacy of ımmune checkpoint blockade therapies in patients with metastatic urothelial carcinoma

Tural, Deniz; Selcukbiricik, Fatih; Olmez, Omer Fatih; Sumbul, Ahmet Taner; Erman, Mustafa; Kilickap, Saadettin (Springer Link, 2021)

Background: Atezolizumab (ATZ) has demonstrated antitumor activity in previous studies in patients with metastatic platinum-resistant urothelial carcinoma. However, the response rate of ATZ was modest. Therefore, finding ...