Now showing items 1-6 of 6
Cervical cancer progression is regulated by SOX transcription factors: Revealing signaling networks and therapeutic strategies
(Elsevier Science, 2021)
Cervical cancer is the fourth common gynecologic cancer and is considered as second leading cause of death among women. Various strategies are applied in treatment of cervical cancer including radiotherapy, chemotherapy ...
Stimuli-responsive liposomal nanoformulations in cancer therapy: Pre-clinical & clinical approaches
The site-specific delivery of antitumor agents is of importance for providing effective cancer suppression. Poor bioavailability of anticancer compounds and the presence of biological barriers prevent their accumulation ...
Non-coding RNAs and macrophage interaction in tumor progression
(Elsevier Ireland Ltd, 2022)
The macrophages are abundantly found in TME and their M2 polarization is in favor of tumor malignancy. On the other hand, non-coding RNAs (ncRNAs) can modulate macrophage polarization in TME to affect cancer progression. ...
NF-κB as a regulator of cancer metastasis and therapy response: A focus on epithelial-mesenchymal transition
Metastasis of tumor cells is a complex challenge and significantly diminishes theoverall survival and prognosis of cancer patients. The epithelial‐to‐mesenchymaltransition (EMT) is a well‐known mechanism responsible for ...
Non-coding RNAs targeting notch signaling pathway in cancer : from proliferation to cancer therapy resistance
(Elsevier B.V., 2022)
Cancer is a challenging to treat disease with a high mortality rate worldwide, nevertheless advances in science has led to a decrease in the number of death cases caused by cancer. Aberrant expression of genes occurs during ...
The long and short non-coding RNAs modulating EZH2 signaling in cancer
Non-coding RNAs (ncRNAs) are a large family of RNA molecules with no capability in encoding proteins. However, they participate in developmental and biological processes and their abnormal expression affects cancer ...