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Prognostic biomarkers in lung cancer patients in terms of long-term survival 

Coskun, Belkis Nihan; Dizdar, Oguzhan Sitki; Korkmaz, Seniz; Ulukaya, Engin; Evrensel, Turkkan (DergiPark, 2021)
Introduction: We aimed to investigate the predictive effect of serum M30 and M65 antigens on long-term prognosis in patients with advanced stage lung cancer before and after the first dose of chemotherapy. Methods: Fourty ...
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Investigation of the efficacy of paclitaxel on some miRNAs profiles in breast cancer stem cells 

Erturk, Elif; Ari, Ferda; Akgun, Oguzhan; Ulukaya, Engin; Kucukali, Cem Ismail; Zeybek, Umit (TUBITAK SCIENTIFIC & TECHNICAL RESEARCH COUNCIL TURKEY, 2021)
Understanding of the functions of microRNAs in breast cancer and breast cancer stem cells have been a hope for the development of new molecular targeted therapies. Here, it is aimed to investigate the differences in the ...
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Structures and anticancer activity of chlorido platinum(II) saccharinate complexes with mono- and dialkylphenylphosphines 

Icsel, Ceyda; Yilmaz, Veysel T.; Cevatemre, Buse; Aygun, Muhittin; Ulukaya, Engin (Elsevier Science Inc, 2019)
cis-[PtCl(sac)(PPh2Me)(2)] (1), cis-[PtCl(sac)(PPhMe2)(2)] (2), trans-[PtCl(sac)(PPh2Et)(2)] (3) and trans- [PtCl(sac) (PPhEt2)(2)] (4) complexes (sac = saccharinate) were synthesized and characterized by elemental analysis ...
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Quantification of DNA damage products by gas chromatography tandem mass spectrometry in lung cell lines and prevention effect of thyme antioxidants on oxidative induced DNA damage 

Aybastier, Onder; Dawbaa, Sam; Demir, Cevdet; Akgun, Oguzhan; Ulukaya, Engin; Ari, Ferda (Elsevier Science Bv, 2018)
Lung cancer has a high treatment cost and poor prognosis in comparison to other types of cancers. This work was involved in studying oxidative DNA base damage inhibition. Accordingly, standard carvacrol, thymol, thymoquinone ...
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Cytotoxic platinum(II) complexes derived from saccharinate and phosphine ligands: synthesis, structures, DNA cleavage, and oxidative stress-induced apoptosis 

Icsel, Ceyda; Yilmaz, Veysel T.; Cevatemre, Buse; Aygun, Muhittin; Ulukaya, Engin (Springer, 2020)
A series of the structurally related platinum(II) saccharinate (sac) complexes with alkylphenylphosphines, namely cis-[Pt(sac)(2)(PPh2Me)(2)]center dot DMSO (1), cis-[Pt(sac)(2)(PPhMe2)(2)] (2), cis-[Pt(sac)(2)(PPh2Et)(2)] ...
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Trans-Pd/Pt(II) saccharinate complexes with a phosphine ligand: Synthesis, cytotoxicity and structure-activity relationship 

Icsel, Ceyda; Yilmaz, Veysel T.; Aygun, Muhittin; Ulukaya, Engin (Pergamon-Elsevier Science Ltd, 2020)
New trans-[Pd(sac)(2)(PPhMe2)(DMSO)]center dot H2O (Pd) and trans-[Pt(sac)(2)(PPhMe2)(2)]center dot H2O (Pt) complexes (sac = saccharinate and PPhMe 2 = dimethylphenylphosphine) were synthesized and characterized by elemental ...
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Preparation and characterization of palladium derivate-loaded micelle formulation in vitro as an innovative therapy option against non-small cell lung cancer cells 

Erkisa, Merve; Ari, Ferda; Buyukkoroglu, Gulay; Senel, Bedriye; Yilmaz, Veysel Turan; Ulukaya, Engin (WILEY, 2021)
Nanoparticles have been used in cancer treatments to target tumor and reduce side effects. In this study, we aimed to increase the effectiveness of palladium(II) complex [PdCl(terpy)](sac)·2H2O, which previously showed ...
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Palladium (II) complex enhances ROS-dependent apoptotic effects via autophagy inhibition and disruption of multiple signaling pathways in colorectal cancer cells 

Aydinlik, Seyma; Erkisa Genel, Merve; Ari, Ferda; Celikler, Serap; Ulukaya, Engin (2021)
Background: Inhibition of autophagy is reported to be a therapeutically effective strategy in overcoming the resistance that is a deadly outcome in cancer. One of the most common reasons for chemo-resistance to treatment ...
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Palladium (II) complex and thalidomide intercept angiogenic signaling via targeting FAK/Src and Erk/Akt/PLC gamma dependent autophagy pathways in human umbilical vein endothelial cells 

Aydinlik, Seyma; Uvez, Ayca; Kiyan, Hulya Tuba; Gurel-Gurevin, Ebru; Yilmaz, Veysel Turan; Ulukaya, Engin (Elsevier, 2021)
The current study assessed the effects of the thalidomide and palladium (II) saccharinate complex of terpyridine on the suppression of angiogenesis-mediated cell proliferation. The viability was assessed after treatment ...
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Structural studies and cytotoxic activity of a new dinuclear coordination compound of palladium(II)-2,2:6,2-terpyridine with rigid dianionic 1,2,4-triazole-3-sulfonate linker 

Buyukeksi, Sebile Isik; Erkisa Genel, Merve; Şengül, Abdurrahman; Ulukaya, Engin; Oral, Arzu Yilmaztepe (Wiley, 2018)
A new dinuclear coordination compound of palladium(II), [Pd-2(terpy)(2)(-tas-N-1,N-4)]SO(4)11H(2)O (1), was synthesized by tethering a doubly deprotonated 1,2,4-triazole-3-sulfonate (tas) linker generated in situ via ...
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Ari, Ferda (20)Cevatemre, Buse (11)Erkisa Genel, Merve (11)Erkisa, Merve (8)Erkısa Genel, Merve (8)Aztopal, Nazlıhan (7)Icsel, Ceyda (7)Karakaş Zeybek, Didem (7)Aydinlik, Seyma (6)... View MoreSubjectApoptosis (20)Cytotoxicity (16)Breast Cancer (8)Autophagy (5)Saccharinate (5)Lung Cancer (4)Anticancer Activity (3)Dna Damage (3)Doxorubicin (3)Epigenetic Modulators (3)... View MoreDate Issued2019 (14)2021 (14)2018 (12)2017 (9)2020 (8)2022 (8)2016 (1)2023 (1)Full Text StatusWith Full Text (62)Without Full Text (5)

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