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Molecular landscape of LncRNAs in prostate cancer: A focus on pathways and therapeutic targets for intervention
(PMC, 2022)
Background: One of the most malignant tumors in men is prostate cancer that is still incurable due to its heterog‑
enous and progressive natures. Genetic and epigenetic changes play signifcant roles in its development. ...
Developing novel hydroxypropyl-β-cyclodextrin-based nanosponges as carriers for anticancer hydrophobic agents: Overcoming limitations of host-guest complexes in a comparative evaluation
(PMC, 2022)
This study aimed to design and fabricate novel hydroxypropyl-β-cyclodextrin-based hypercrosslinked polymers, called nanosponges, as carriers for anticancer hydrophobic agents and
compare them with host–guest complexes of ...
Multilayered mesoporous composite nanostructures for highly sensitive label-free quantification of cardiac troponin-I
(PMC, 2022)
Cardiac troponin-I (cTnI) is a well-known biomarker for the diagnosis and control of
acute myocardial infarction in clinical practice. To improve the accuracy and reliability of cTnI
electrochemical immunosensors, we ...
Gene editing-based technologies for beta-hemoglobinopathies treatment
(MDPI, 2022)
Simple Summary: β-thalassemia syndromes are clinically and genetically heterogeneous blood
disorders presented by β-chain deficiency in hemoglobin production. Despite improvements in
transfusion practices and chelation ...
Exosomes as promising nanostructures in diabetes mellitus: from insulin sensitivity to ameliorating diabetic complications
(2022)
Diabetes mellitus (DM) is among the chronic metabolic disorders that its incidence rate has shown an increase in developed and wealthy countries due to lifestyle and obesity. The treatment of DM has always been of interest, ...
Targeting Nrf2 in ischemia-reperfusion alleviation: From signaling networks to therapeutic targeting
(Elsevier Inc., 2022)
The nuclear factor erythroid 2-related factor 2 (Nrf2) is a master regulator of redox balance and it responds to various cell stresses that oxidative stress is the most well-known one. The Nrf2 should undergo nuclear ...
Emerging role of exosomes in cancer progression and tumor microenvironment remodeling
(BioMed Central, 2022)
Cancer is one of the leading causes of death worldwide, and the factors responsible for its progression need to be elucidated. Exosomes are structures with an average size of 100 nm that can transport proteins, lipids, and ...
Nanotechnology for SARS-CoV-2 diagnosis
(DE GRUYTER POLAND SP Z O O, 2022)
As the first cause of death in the last three years, SARS-CoV-2 infection gained lots of interest. In light of this, several studies have been done to fabricate novel, high-speed detection methods for different virus ...
Graphene oxide quantum dot-chitosan nanotheranostic platform as a pH-responsive carrier for improving curcumin uptake internalization: In vitro & in silico study
(Elsevier, 2022)
We herein fabricated a cancer nanotheranostics platform based on Graphene Oxide Quantum Dot-Chitosan-polyethylene glycol nanoconjugate (GOQD-CS-PEG), which were targeted with MUC-1 aptamer towards breast and colon tumors. ...
Nanotechnological approaches in prostate cancer therapy: Integration of engineering and biology
(Elsevier B.V., 2022)
Nanocarriers have received special attention in biomedicine for the treatment of various diseases, especially cancer, as one of the leading causes of death worldwide. Nanocarriers can improve the potential of contemporary ...
