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Baicalein ve thymoquinone kombinasyounun akciğer kanseri hücre hattı üzerindeki sitotoksit ve apoptotik etkilerinin araştırılması
(İstinye Üniversitesi / Sağlık Bilimleri Enstitüsü, 2021)
Akciğer kanseri dünya çapında önde gelen ölüm nedenidir. Kemoterapi tedavi sonrası
hücrelerde meydana gelen direnç, kanser ölümlerin çoğalmasının nedenidir. Bu nedenle
akciğer kanseri tedavisinde yönelik yeni ilaç ve ...
Spironolakton ve timokinon kombinasyonununakciğer kanseri hücre soylarındasitotoksik/apoptotik etkilerinin araştırılması
(İstinye Üniversitesi / Sağlık Bilimleri Enstitüsü, 2021)
Akciğer kanseri dünyada en çok yanıt verilen kanserdir. Kanserde kemoterapi,
radyoterapi ve immünoterapi tedavisinin etkinliği, hastaların tedaviye direnç
geliştirdiği ve tümörlerinin birbirinden tamamen farklı olduğu ...
Gallic acid for cancer therapy: molecular mechanisms and boosting efficacy by nanoscopical delivery
(Elsevier, 2021)
Cancer is the second leading cause of death worldwide. Majority of recent research efforts in the field aim to address why cancer resistance to therapy develops and how to overcome or prevent it. In line with this, novel ...
Dual akt and bcl-2 inhibition induces cell-type specific modulation of apoptotic and autophagic signaling in castration resistant prostate cancer cell lines
(Springer Nature, 2021)
Cancer cell survival depends on the cross-regulation between apoptosis and autophagy which share common signaling pathways including PI3K/Akt/mTOR and Bcl-2. The aim of this study was to elucidate the modulation patterns ...
Serum survivin is decreased in women with preeclampsia
(Taylor & Francis Online, 2021)
Objective: To evaluate the serum survivin level in preeclampsia.Methods: Eighty-eight pregnancies complicated with preeclampsia and 88 gestational-age (GA)-matched uncomplicated pregnancies were evaluated.Results: Mean ...
Naftakinon türevli yeni sentez bileşiklerin kanser hücre hatları üzerine etkisinin incelenmesi
(İstinye Üniversitesi / Sağlık Bilimleri Enstitüsü, 2020)
Prostat kanseri dünyada ikinci, İskandinavya da dahil gelişmiş ülkelerde ise en sık
rastlanan birinci kanser türüdür. Hormon ve/veya kemoterapi tedavisi sonrası
hücrelerde meydana gelen direnç kanser kaynaklı ölümlerin ...
Targeting AMPK signaling in ischemic/reperfusion injury: From molecular mechanism to pharmacological interventions
(2022)
Ischemia is a pathological process in which blood supply to a particular organ is temporarily interrupted resulting in disturbed biological function and homeostasis of local tissues. Following ischemia, reperfusion and ...
The apoptotic effect of ozone therapy on mitochondria of highly metastatic breast cancer cell line MDA-MB-231 using in vitro approaches
(KeAi, 2022)
Ozone (O3) gas is the triatomic state of oxygen and it is used as a disinfection agent due to its strong oxidizing
effect, since its discovery in the mid-nineteenth century. Ozone therapy is also an alternative therapeutic ...
A focusing study on radioprotective and antioxidant effects of Annona muricata leaf extract in the circulation and liver tissue: clinical and experimental studies
(De Gruyter Open Ltd, 2022)
Objectives: This study investigates the effect of Annona muricata (AM) leaf extract against irradiation-induced damage by the evaluation of hepatic tissue and the levels of oxidative and inflammatory stress in the circulation. ...
Clinical comprehensive and experimental assessment of the radioprotective effect of Annona muricata leaf extract to prevent cellular damage in the ileum tissue
(De Gruyter Open Ltd, 2022)
We report the radioprotective attitude of Annona muricata (AM) leaf extract as antioxidant material to prevent cellular damage in the ileum tissue. The protective effects of an ethyl acetate extract of AM leaves are ...
