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Comparison of different sources of mesenchymal stem cells: palatal versus lipoaspirated adipose tissue
(Karger, 2017)
Objectives: The purpose of this study was to compare the proliferation and differentiation potential of mesenchymal stem cells (MSCs) derived from palatal adipose tissue (PAT) and lipoaspirated adipose tissue (LAT). Materials ...
Mesenchymal stem cells treatment in COVID-19 patient with multi-organ involvement
(COMENIUS UNIV, 2020)
The aim of this study is to evaluate the therapeutic effect of mesenchymal stem cells (MSCs) in a severe case of brain and multiple organ involvement in a patient with COVID-19. Here, a 51-year-old male patient with ...
Improving effects of mesenchymal stem cells on symptoms of chronic obstructive pulmonary disease
(Comenius Univ, 2020)
AIM: We aimed to identify the improving effects of umbilical cord tissue-derived (UCTD) MSCs on the symptoms of COPD in our phase 1.2 clinical study. MATERIAL METHODS: Our study consisted of five patients with COPD. ...
Neuronal regeneration in injured rat spinal cord after human dental pulp derived neural crest stem cell transplantation
(Comenius Univ, 2018)
OBJECTIVE: This study aimed to analyze the effect of human Dental Pulp-Neural Crest Stem Cells (hDP-NCSCs) delivery on lesion site after spinal cord injury (SCI), and to observe the functional recovery after transplantation. ...
Combinations of wharton Jelly derived exosomes and salicylic acid: A new hope for eradication of cutaneous leishmaniasis
(PARLAR SCIENTIFIC PUBLICATIONS, 2022)
The aim of the current study is to obtain wharton jelly derived exosomes, prepare therapeutic formulations including combinations of isolated exosomes and salicylic acid, investigate their in vitro antileishmanial activities ...
Comparative proteomics analysis of four commonly used methods for identification of novel plasma membrane proteins
(Springer, 2019)
Plasma membrane proteins perform a variety of important tasks in the cells. These tasks can be diverse as carrying nutrients across the plasma membrane, receiving chemical signals from outside the cell, translating them ...
Genomic and proteomic monitoring of stem cell-derived exosomes
(HUMANA PRESS INC, 2019)
The mesenchymal stem cell (MSC) transplantations are increasing day by day in clinical therapies. Recent studies have described that the treatment activities of MSCs are mediated by paracrine factors secreted. These paracrine ...
Calvarial bone defects in ovariectomised rats treated with mesenchymal stem cells and demineralised freeze-dried bone allografts
(NLM (Medline), 2020)
BACKGROUND: The aim of the study was to investigate the ability of a combination of bone marrow mesenchymal stem cells (BM-MSCs) with and without demineralised freeze-dried bone allografts (DFDBAs) to induce bone regeneration ...
Isolation, culture, cryopreservation, and preparation of umbilical cord-derived mesenchymal stem cells as a final cellular product under good manufacturing practices-compliant conditions
(2021)
Mesenchymal stem cells have gained popularity in cell-based therapies due to their regenerative capabilities, immunomodulation properties, and paracrine activity through trophic factors. It is of utmost importance to ...
Validation of the media fill method for solid tissue processing in good manufacturing practice-compliant cell production
(2021)
Over the past few years, a large number of clinical studies for advanced therapy medicinal products have been registered and/or conducted for treating various diseases around the world and many have generated very exciting ...
