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Can Wharton jelly derived or adipose tissue derived mesenchymal stem cell can be a treatment option for duchenne muscular dystrophy? Answers as transcriptomic aspect
(E-CENTURY PUBLISHING CORP, 2020)
Introduction: Mesenchymal stem cells (MSCs) are able to differentiate into several cell lineages including skeletal muscle. In addition to their differentiation capacities, they have the ability to transfer their content ...
The paracrine immunomodulatory interactions between the human dental pulp derived mesenchymal stem cells and CD4 T cell subsets
(Academic Press Inc Elsevier Science, 2016)
Mesenchymal stem cells (MSCs) have strong immunomodulatory properties, however these properties may show some differences according to the tissue type of their isolate. In this study we investigated the paracrine interactions ...
Age-related changes in the immunomodulatory effects of human dental pulp derived mesenchymal stem cells on the CD4 + T cell subsets
(2021)
Mesenchymal stem cells (MSCs) are powerful immunomodulatory cells. The effects of the aging on these abilities of MSCs have not been adequately clarified. In this study, alterations in immunomodulatory abilities of MSCs ...
Olfactory ensheathing cells: unique glial cells promising for treatments of spinal cord injury
(Wiley, 2021)
Spinal cord injury (SCI) is generally the consequence of physical damage, which may result in devastating consequences such as paraplegia or paralysis. Some certain candidates for SCI repair are olfactory ensheathing cells ...
Generation of induced pluripotent stem cells from patients with multiple myeloma
(gelenos, 2021)
Yamanaka and Takahashi made a discovery in the world of life science by transforming mouse
somatic fibroblasts into pluripotent cells as a result of transferring 4 gene sets (Sox2-Oct4-
Klf4&c-Myc) in 2006 (1). Since ...
SDF-1 modulates periodontal ligament-Mesenchymal Stem Cells (pdl-MSCs)
(WILEY, 2021)
Background/objectives: In this in vitro study, the effects of Stromal cell-derived factor-1 (SDF-1) was evaluated on the periodontal ligament-Mesenchymal Stem Cells (pdl-MSCs) functions.
Material and methods: Real-time ...
Isolation, culture, cryopreservation, and preparation of umbilical cord-derived mesenchymal stem cells as a final cellular product under good manufacturing practices-compliant conditions
(2021)
Mesenchymal stem cells have gained popularity in cell-based therapies due to their regenerative capabilities, immunomodulation properties, and paracrine activity through trophic factors. It is of utmost importance to ...
Isolation, culture, cryopreservation, and preparation of skin-derived fibroblasts as a final cellular product under good manufacturing practice-compliant conditions
(2021)
Cell-based therapies have become a popular approach in the field of regenerative medicine. Human fibroblast cells, one of the cell types widely used in clinical applications, have been used for skin regeneration and wound ...
Validation of the media fill method for solid tissue processing in good manufacturing practice-compliant cell production
(2021)
Over the past few years, a large number of clinical studies for advanced therapy medicinal products have been registered and/or conducted for treating various diseases around the world and many have generated very exciting ...
Contribution of bone marrow–derived mesenchymal stem cells to healing of pulmonary contusion-created rats
(Academic Press Inc., 2021)
Background: The most common thoracic injury in children, resulting in trauma, is pulmonary contusion (PC). Bone marrow–derived mesenchymal stem cells (BM-MSCs) are used in wound healing and many other diseases. This study ...
