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Phase I study on the safety and preliminary efficacy of allogeneic mesenchymal stem cells in hypoxic-ischemic encephalopathy
(Baishideng Publishing Group Co, 2021)
BACKGROUND Hypoxic-ischemic encephalopathy (HIE) is a leading cause of morbidity and mortality in the adult as well as in the neonate, with limited options for treatment and significant dysfunctionality. AIM To investigate ...
Functional recovery after wharton’s jelly–derived mesenchymal stem cell administration in a patient with traumatic spinal cord injury: a pilot study
(Gelenos, 2021)
The use of stem cells in the treatment of traumatic spinal cord injury (SCI) in recent years has provided promising results. Different sources
of cells for transplantation have been used, including mesenchymal stem cells ...
Genomic and proteomic monitoring of stem cell-derived exosomes
(HUMANA PRESS INC, 2019)
The mesenchymal stem cell (MSC) transplantations are increasing day by day in clinical therapies. Recent studies have described that the treatment activities of MSCs are mediated by paracrine factors secreted. These paracrine ...
Wound treatment by stem cells
(SPRINGER INTERNATIONAL PUBLISHING AG, 2017)
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Feasibility of allogeneic mesenchymal stem cells in pediatric hypoxic-ischemic encephalopathy: phase I study
(Baishideng Publishing Group Co, 2021)
Background Hypoxic-ischemic encephalopathy (HIE) is one of the leading causes of death and long-term neurological impairment in the pediatric population. Despite a limited number of treatments to cure HIE, stem cell therapies ...
Effects of VEGF plus adipose tissue derived mesenchymal stem cells with platelet rich plasma on inbred rat ovarian functions in premature ovarian insufficiency model
(Oxford Univ Press, 2017)
What is known already: Numerous studies have found an increased risk of congenital malformations among live-born children conceived after assisted reproduction compared with spontaneously conceivedchildren. The underlying ...
Age-related changes in the immunomodulatory effects of human dental pulp derived mesenchymal stem cells on the CD4 + T cell subsets
(2021)
Mesenchymal stem cells (MSCs) are powerful immunomodulatory cells. The effects of the aging on these abilities of MSCs have not been adequately clarified. In this study, alterations in immunomodulatory abilities of MSCs ...
Safety and efficacy of the stem cell transplantation in friedreich's ataxia: a report of three cases
(IJPHY PUBLISHERS, 2021)
Background: Friedreich's ataxia is a progressive degenerative disorder caused by deficiency of the frataxin protein. Expanded GAA repeats in intron 1 of the FXN gene lead to its heterochromatinization and transcriptional ...
Stem cell based therapy option in COVID-19: is it really promising?
(INT SOC AGING & DISEASE, 2020)
The COVID-19 patients were first detected in China, in December 2019, then the novel virus with associated pneumonia and other diseases spread quickly to worldwide becoming a serious public health intimidation. Despite all ...
Histopathological, immunohistochemical, and biomechanical effects of splenectomy on Achilles tendon healing in rats
(Taylor & Francis Inc, 2019)
Purpose: This study aimed to assess Achilles tendon repair in rats following splenectomy to simulate patients with musculoskeletal system injury who had splenectomy after spleen injury, a situation often seen in orthopedics ...
