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Age-related changes in the immunomodulatory effects of human dental pulp derived mesenchymal stem cells on the CD4 + T cell subsets
(2021)
Mesenchymal stem cells (MSCs) are powerful immunomodulatory cells. The effects of the aging on these abilities of MSCs have not been adequately clarified. In this study, alterations in immunomodulatory abilities of MSCs ...
Mesenchymal stem cells increase antioxidant capacity in intestinal ischemia/reperfusion damage
(W B Saunders Co-Elsevier Inc, 2017)
Background: Mesenchymal stemcells (MSCs) may have beneficial effects in reversing intestinal damage resulting fromcirculatory disorders. The hypothesis of this study is thatMSCs increase antioxidant capacity of small bowel ...
Mesenchymal stem cell-derived exosomes do not promote the proliferation of cancer cells in vitro
(2019)
Nowadays, the use of Mesenchymal stem cells (MSCs) in clinical therapies have an increased acceleration, while it constitutes two sides of yin-yang with its ameliorating effects in regenerative medicine and promoting effects ...
Comparison of mesenchymal stem cell sheets and chondrocyte sheets in a rabbit growth plate injury model
(Tubitak Scientific & Technical Research Council Turkey, 2020)
Background/aim: The treatment of posttraumatic deformities and differences in length between the extremities resulting from physeal injury remains controversial. The aims of this study were to compare the efficacy of ...
The effect of umbilical cord-derived mesenchymal stem cell transplantation in a patient with cerebral palsy: a case report
(Korean Soc Stem Cell Research, 2018)
Background: Cerebral Palsy (CP) is the most common motor disability reason of childhood that occurs secondarily to non-progressive damage in the brain whose development is still ongoing. Methods: 6-year-old dystonic-spastic ...
The paracrine immunomodulatory interactions between the human dental pulp derived mesenchymal stem cells and CD4 T cell subsets
(Academic Press Inc Elsevier Science, 2016)
Mesenchymal stem cells (MSCs) have strong immunomodulatory properties, however these properties may show some differences according to the tissue type of their isolate. In this study we investigated the paracrine interactions ...
The effect of recombinant tyrosine hydroxylase expression on the neurogenic differentiation potency of mesenchymal stem cells
(Korean Spinal Neurosurgery Soc, 2018)
Objective: Tyrosine hydroxylase (TH) is a rate-limiting enzyme in dopamine synthesis, making the enhancement of its activity a target for ensuring sufficient dopamine levels. Rat bone marrow mesenchymal stem cells (rBM-MSCs) ...
Mesenchymal stem cells treatment in COVID-19 patient with multi-organ involvement
(COMENIUS UNIV, 2020)
The aim of this study is to evaluate the therapeutic effect of mesenchymal stem cells (MSCs) in a severe case of brain and multiple organ involvement in a patient with COVID-19. Here, a 51-year-old male patient with ...
Combinations of wharton Jelly derived exosomes and salicylic acid: A new hope for eradication of cutaneous leishmaniasis
(PARLAR SCIENTIFIC PUBLICATIONS, 2022)
The aim of the current study is to obtain wharton jelly derived exosomes, prepare therapeutic formulations including combinations of isolated exosomes and salicylic acid, investigate their in vitro antileishmanial activities ...