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Long non-coding RNAs and exosomal incRNAs: Potential functions in lung cancer progression, drug resistance and tumor microenvironment remodeling

Entezari, Maliheh; Ghanbarirad, Maryam; Taheriazam, Afshin; Sadrkhanloo, Mehrdokht; Zabolian, Amirhossein; Shekhi Beig Goharrizi, Mohammad Ali; Hushmandi, Kiavash; Aref, Amir Reza; Ashrafizadeh, Milad; Zarrabi, Ali; Nabavi, Noushin; Rabiee, Navid; Hashemi, Mehrdad; Samarghandian, Saeed (Elsevier Science, 2022)

Among the different kinds of tumors threatening human life, lung cancer is one that is commonly observed in both males and females. The aggressive behavior of lung cancer and interactions occurring in tumor microenvironment ...

Non-coding RNAs and macrophage interaction in tumor progression

Entezari, Maliheh; Sadrkhanloo, Mehrdokht; Rashidi, Mohsen; Asnaf, Sholeh Etehad; Taheriazam, Afshin; Hashemi, Mehrdad; Ashrafizadeh, Milad; Zarrabi, Ali; Rabiee, Navid; Hushmandi, Kiavash; Mirzaei, Sepideh; Sethi, Gautam (Elsevier Ireland Ltd, 2022)

The macrophages are abundantly found in TME and their M2 polarization is in favor of tumor malignancy. On the other hand, non-coding RNAs (ncRNAs) can modulate macrophage polarization in TME to affect cancer progression. ...

Molecular landscape of LncRNAs in prostate cancer: A focus on pathways and therapeutic targets for intervention

Mirzaei, Sepideh; Abad Paskeh, Mahshid Deldar; Okina, Elena; Gholami, Mohammad Hossein; Hushmandi, Kiavash; Hashemi, Mehrdad; Kalu , Azuma; Zarrabi, Ali; Nabav, Noushin; Rabiee, Navid; Sharifi, Esmaeel; Karimi-Maleh, Hassan; Ashrafizadeh, Milad; Kumar, Alan Prem; Wang, Yuzhuo (PMC, 2022)

Background: One of the most malignant tumors in men is prostate cancer that is still incurable due to its heterog‑ enous and progressive natures. Genetic and epigenetic changes play signifcant roles in its development. ...

Long noncoding RNAs (lncRNAs) in pancreatic cancer progression

Ashrafizadeh, Milad; Rabiee, Navid; Prem Kumar, Alan; Sethi, Gautam; Zarrabi, Ali; Wang, Yuzhuo (Elsevier Science, 2022)

Long noncoding RNAs (lncRNAs) are RNA molecules involved in gene regulation at transcriptional, post-transcriptional, and epigenetic levels. lncRNAs participate in regulating apoptosis and autophagy in pancreatic cancer ...

Long non-coding RNAs and exosomal lncRNAs: Potential functions in lung cancer progression, drug resistance and tumor microenvironment remodeling

Entezari, Maliheh; Ghanbarirad, Maryam; Taheriazam, Afshin; Sadrkhanloo, Mehrdokht; Zabolian, Amirhossein; Goharrizi, Mohammad Ali Shekhi Beig; Hushmandi, Kiavash; Aref, Amir Reza; Ashrafizadeh, Milad; Zarrabi, Ali; Nabavi, Noushin; Rabiee, Navid; Hashemi, Mehrdad; Samarghandian, Saeed (Elsevier, 2022)

Chitosan-based nanoscale systems for doxorubicin delivery: Exploring biomedical application in cancer therapy

Ashrafizadeh, Milad; Hushmandi, Kiavash; Mirzaei, Sepideh; Bokaie, Saied; Bigham, Ashkan; Makvandi, Pooyan; Rabiee, Navid; Thakur, Vijay Kumar; Kumar, Alan Prem; Sharifi, Esmaeel; Varma, Rajender S.; Aref, Amir Reza; Wojnilowicz, Marcin; Zarrabi, Ali; Karimi-Maleh, Hassan; Voelcker, Nicolas H.; Mostafavi, Ebrahim; Orive, Gorka (AICHE Online Library, 2022)

Green chemistry has been a growing multidisciplinary field in recent years showing great promise in biomedical applications, especially for cancer therapy. Chitosan (CS) is an abundant biopolymer derived from chitin and ...

Customizing nano-chitosan for sustainable drug delivery

Mostafa Saeedi 1, Omid Vahidi 1, Mohammadreza Moghbeli 1, Sepideh Ahmadi 2, Mohsen Asadnia 3, Omid Akhavan 4, Farzad Seidi 5, Mohammad Rabiee 6, Mohammad Reza Saeb 7, Thomas J Webster 8, Rajender S Varma 9, Esmaeel Sharifi 10, Ali Zarrabi 11, Navid Rabiee 12 Affiliations collapse; Saeedi, Mostafa; Vahidi, Omid; Moghbeli, Mohammadreza; Ahmadi, Sepideh; Asadnia, Mohsen; Akhavan, Omid; Seidi, Farzad; Rabiee, Mohammad; Saeb, Mohammad Reza; Webster, Thomas J.; Zarrabi, Ali; Rabiee, Navid; Varma, Rajender S.; Sharifi, Esmaeel (PMC, 2022)

Chitosan is a natural polymer with acceptable biocompatibility, biodegradability, and mechanical stability; hence, it has been widely appraised for drug and gene delivery applications. However, there has been no comprehensive ...

Stimuli-responsive liposomal nanoformulations in cancer therapy: Pre-clinical & clinical approaches

Ashrafizadeh, Milad; Delfi, Masoud; Zarrabi, Ali; Sharifi, Esmaeel; Rabiee, Navid; Paiva-Santos, Ana Cláudia; Kumar, Alan Prem; Hushmandi, Kiavash; Nazarzadeh Zare, Ehsan; Makvandi, Pooyan (Elsevier, 2022)

The site-specific delivery of antitumor agents is of importance for providing effective cancer suppression. Poor bioavailability of anticancer compounds and the presence of biological barriers prevent their accumulation ...

Magnetic nanocomposites for biomedical applications

Naghdi, Mina; Ghovvati, Mahsa; Rabiee, Navid; Ahmadi, Sepideh; Abbariki, Nikzad; Sojdeh, Soheil; Ojaghi, Amirhossein; Bagherzadeh, Mojtaba; Akhavan, Omid; Sharifi, Esmaeel; Rabiee, Mohammad; Saeb, Mohammad Reza; Bolouri, Keivan; Webster, Thomas J.; Zare, Ehsan Nazarzadeh; Zarrabi, Ali (Elsevier B.V., 2022)

Tissue engineering and regenerative medicine have solved numerous problems related to the repair and regeneration of damaged organs and tissues arising from aging, illnesses, and injuries. Nanotechnology has further aided ...

Advances in aptamer-based drug delivery vehicles for cancer therapy

Ghasemi, Kousar; Darroudi, Mahdieh; Rahimmanesh, Ilnaz; Ghomi, Matineh; Hassanpour, Mahnaz; Sharifi, Esmaeel; Yousefiasl, Satar; Ahmadi, Sepideh; Zarrabi, Ali; Borzacchiello, Assunta; Rabiee, Mohammad; Paiva-Santos, Ana Cláudia; Rabiee, Navid (Elsevier, 2022)

Overall, aptamers are special classes of nucleic acid-based macromolecules that are beginning to investigate because of their capability of avidity binding to a specific target for clinical use. Taking advantage of ...