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Hematopoetic stem cell transplantation in CD40 ligand deficiency

Uygun, Vedat; Uygun, Dilara Fatma Kocacik; Daloglu, Hayriye; Ozturkmen, Seda; Kilic, Suar Caki; Bingol, Aysen; Yalcin, Koray; Celen, Safiye Suna; Hazar, Volkan; Tezcan Karasu, Gulsun; Yesilipek, Akif (SPRINGERNATURE, 2020)

[No Abstract]

Pearson syndrome in a patient transplanted for diamond-blackfan anemia

Tezcan Karasu, Gulsun; Uygun, Vedat; Daloglu, Hayriye; Ozturkmen, Seda; Yesilipek, Akif (SPRINGERNATURE, 2020)

[No Abstract]

Hematopoietic stem cell transplantation in CD40 ligand deficiency: a single-center experience

Uygun, Dilara Fatma Kocacik; Uygun, Vedat; Tezcan Karasu, Gulsun; Daloglu, Hayriye; Ozturkmen, Seda Irmak; Celmeli, Fatih; Torun, Selda Hancerli; Ozen, Ahmet; Baris, Safa; Aydiner, Elif Karakoc; Yalcin, Koray; Kilic, Suar Caki; Hazar, Volkan; Bingol, Aysen; Yesilipek, Akif (Wiley, 2020)

Deficiency of the CD40L, expressed on the surface of T lymphocytes, is caused by mutations in the glycoproteinCD40L (CD154)gene. Resulting defective humoral and cellular responses cause a clinical presentation that includes ...

Ruxolitinib salvage therapy is effective for steroid-refractory graft-versus-host disease in children: a single-center experience

Uygun, Vedat; Tezcan Karasu, Gulsun; Daloglu, Hayriye; Ozturkmen, Seda; Kilic, Suar Caki; Yalcin, Koray; Celen, Safiye Suna; Hazar, Volkan; Yesilipek, Akif (Wiley, 2020)

Background Despite the increasing performance of allogeneic hematopoietic cell transplantation over the last decades, graft-versus-host disease (GVHD) remains the main cause of morbidity and mortality. The efficacy of ...

Prognostic factors for survival in children who relapsed after allogeneic hematopoietic stem cell transplantation for acute leukemia

Hazar, Volkan; Tezcan Karasu, Gulsun; Ozturk, Gulyuz; Kupesiz, Alphan; Aksoylar, Serap; Ozbek, Namık; Uygun, Vedat; Ileri, Talia; Okur, Fatma Visal; Kocak, Ulker; Caki Kilic, Suar; Akcay, Arzu; Guler, Elif; Kansoy, Savas; Karakukcu, Musa; Bayram, Ibrahim; Aksu , Tekin; Yesilipek, Akif; Karagun, Barbaros Sahin; Yilmaz, Sebnem; Ertem, Mehmet; Uckan, Duygu; Fisgin, Tunc; Gursel, Orhan; Yaman, Yöntem; Bozkurt, Ceyhun; Gokce, Muge (2020)

Background: Post-transplant relapse has a dismal prognosis in children with acute leukemia undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT). Data on risk factors, treatment options, and outcomes ...

Use of low cell dose for unmanipulated donor lymphocyte for management of cytomegalovirus infection: a single-center experience

Uygun, Vedat; Tezcan Karasu, Gulsun; Daloglu, Hayriye; Ozturkmen, Seda; Yalcın, Koray; Celen, Safiye Suna; Yesilipek, Akif (2020)

Although advancements have been made in monitoring and preventing viral infections in HSCT patients, CMV reactivation still remains a critical post-transplant complication. Adoptive cell therapy is an alternative to ...

ILC3 deficiency and generalized ILC abnormalities in DOCK8-deficient patients

Eken, Ahmet; Cansever, Murat; Okus, Fatma Zehra; Erdem, Serife; Nain, Ercan; Azizoglu, Zehra Busra; Haliloglu, Yesim; Karakukcu, Musa; Ozcan, Alper; Devecioglu, Omer; Aksu, Guzide; Arikan Ayyildiz, Zeynep; Topal, Erdem; Karakoc Aydiner, Elif; Kiykim, Ayca; Metin, Ayse; Erol Cipe, Funda; Kaya, Aysenur; Artac, Hasibe; Reisli, Ismail; Guner, Sukru N.; Uygun, Vedat; Tezcan Karasu, Gulsun; Doenmez Altuntas, Hamiyet; Canatan, Halit; Oukka, Mohamed; Ozen, Ahmet; Chatila, Talal A.; Keles, Sevgi; Baris, Safa; Unal, Ekrem; Patiroglu, Turkan (Wiley, 2020)

BackgroundDedicator of cytokinesis 8 (DOCK8) deficiency is the main cause of the autosomal recessive hyper-IgE syndrome (HIES). We previously reported the selective loss of group 3 innate lymphoid cell (ILC) number and ...