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Epigenetic modulators combination with chemotherapy in breast cancer cells
(Wiley, 2021)
Despite the concerning adverse effects on tumour development, epigenetic drugsare very promising in cancer treatment. The aim of this study was to compare the dif-ferential effects of standard chemotherapy regimens (FEC: ...
Soloxolone methyl, as a 18βH-glycyrrhetinic acid derivate, may result in endoplasmic reticulum stress to induce apoptosis in breast cancer cells
(Elsevier Ltd, 2021)
Being one of the leading causes of cancer death among women, various chemotherapeutic agents isolated from natural compounds are used in breast cancer treatment and consequently studies to develop new drugs still continue. ...
Prognostic biomarkers in lung cancer patients in terms of long-term survival
(DergiPark, 2021)
Introduction: We aimed to investigate the predictive effect of serum M30 and M65 antigens on long-term prognosis in patients with advanced stage lung cancer before and after the first dose of chemotherapy. Methods: Fourty ...
Investigation of the efficacy of paclitaxel on some miRNAs profiles in breast cancer stem cells
(TUBITAK SCIENTIFIC & TECHNICAL RESEARCH COUNCIL TURKEY, 2021)
Understanding of the functions of microRNAs in breast cancer and breast cancer stem cells have been a hope for the development of new molecular targeted therapies. Here, it is aimed to investigate the differences in the ...
Preparation and characterization of palladium derivate-loaded micelle formulation in vitro as an innovative therapy option against non-small cell lung cancer cells
(WILEY, 2021)
Nanoparticles have been used in cancer treatments to target tumor and reduce side effects. In this study, we aimed to increase the effectiveness of palladium(II) complex [PdCl(terpy)](sac)·2H2O, which previously showed ...
Palladium (II) complex enhances ROS-dependent apoptotic effects via autophagy inhibition and disruption of multiple signaling pathways in colorectal cancer cells
(2021)
Background: Inhibition of autophagy is reported to be a therapeutically effective strategy in overcoming the resistance that is a deadly outcome in cancer. One of the most common reasons for chemo-resistance to treatment ...
Palladium (II) complex and thalidomide intercept angiogenic signaling via targeting FAK/Src and Erk/Akt/PLC gamma dependent autophagy pathways in human umbilical vein endothelial cells
(Elsevier, 2021)
The current study assessed the effects of the thalidomide and palladium (II) saccharinate
complex of terpyridine on the suppression of angiogenesis-mediated cell proliferation. The
viability was assessed after treatment ...
Water-soluble silver(I) complexes with N-donor benzimidazole ligands containing an imidazolium core: stability and preliminary biological studies
(Royal Society of Chemistry, 2021)
Herein, we report the synthesis, characterisation and preliminary biological evaluation of two novel silver(I) complexes of type [AgL2](NO3)3 (3 and 4) with ionic N-donor benzimidazoles. The complexes have been synthesized ...
Lichens exerts an anti-proliferative effect on human breast and lung cancer cells through induction of apoptosis
(Taylor and Francis Ltd, 2021)
Successful cancer treatment still requires new complexes or compounds from natural sources. Therefore, we investigated anti-growth/apoptotic effects of methanol extracts of the lichen species (Xanthoparmelia somloensis ...
Anticancer potential of albumin bound wnt/beta-catenin pathway inhibitor niclosamide in breast cancer cells
(WILEY, 2021)
Albumin-based nanoparticle transport systems (nab-technology) are a new strategy in cancer treatment and we aimed to increase the effectiveness of Niclosamide using this technology. Niclosamide was bound with bovine serum ...
