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Assessment of the effect of endocrine abnormalities on biomacromolecules and lipids by FT-IR and biochemical assays as biomarker of metabolites in early Polycystic ovary syndrome women

Guleken, Zozan; Bulut, Huri; Bulut, Berk; Depciuch, Joanna (Elsevier, 2021)

Polycystic ovary syndrome (PCOS) is a common endocrinopathy associated with metabolic disturbances.Both in the development and improvement of the disease, the structure of phospholipids and proteinsin the blood serum plays ...

Assessment of structural protein expression by FTIR and biochemical assays as biomarkers of metabolites response in gastric and colon cancer

Guleken, Zozan; Bulut, Huri; Gültekin, Güldal İnal; Arikan, Soykan; Yaylim, Ilhan; Hakan, Mehmet Tolgahan; Sönmez, Dilara; Tarhan, Nevzat K.; Depciuch, Joanna (Elsevier B.V., 2021)

Colon and gastric cancers are the widespread benign types of cancers which are synchronous and metachronous neoplasms. In terms of the progression and progress of the disease, metabolic processes and differentiation in ...

Conserved amino acid residues that affect structural stability of candida boidinii formate dehydrogenase

Bulut, Huri; Yuksel, Busra; Gul, Mehmet; Eren, Meryem; Karatas, Ersin; Kara, Nazli; Yilmazer, Berin; Kocyigit, Abdurrahim; Labrou, Nikolaos E.; Bi̇nay, Barıs Is (Springer, 2021)

The NAD+-dependent formate dehydrogenase (FDH; EC 1.2.1.2) from Candida boidinii (CboFDH) has been extensively used in NAD(H)-dependent industrial biocatalysis as well as in the production of renewable fuels and chemicals ...

Spectrochemical and biochemical assay comparison study of the healing effect of the aloe vera and hypericum perforatum loaded nanofiber dressings on diabetic wound

Guleken, Zozan; Depciuch, Joanna; Ege, Hasan; Ilbay, Gul; Kalkandelen, Cevriye; Ozbeyli, Dilek; Bulut, Huri; Tarhan, Nevzat; Erdem Kuruca, Serap (Elsevier, 2021)

Diabetic wounds have a slow healing process and easy to be infected. In addition to current drug treatments, supportive approaches are needed for diabetic wound treatment. In this study, we aimed to load Aloe Vera (AV) and ...

Serum kallistatin level is decreased in women with preeclampsia

Guralp, Onur; Tuten, Nevin; Gok, Koray; Hamzaoglu, Kubra; Bulut, Huri; Schild-Suhren, Meike; Malik, Eduard; Tuten, Abdullah (2021)

Objective To evaluate the serum levels of the serine proteinase inhibitor kallistatin in women with preeclampsia (PE). Methods The clinical and laboratory parameters of 55 consecutive women with early-onset PE (EOPE) and ...

A low direct electrical signal attenuates oxidative stress and inflammation in septic rats

Ustunova, Savas; Haciosmanoglu, Ebru; Bulut, Huri; Elibol, Birsen; Kilic, Aysu; Hekimoglu, Rumeysa (PMC, 2021)

Electrical stimulation is proposed to exert an antimicrobial effect according to studies performed using bacterial and cell cultures. Therefore, we investigated the effects of electrification on inflammation in septic rats. ...

Angiotensin IV improves spatial memory in streptozotocin‑induced diabetic rats by reducing oxidative stress and altering BDNF levels

Kilic, Aysu; Ustunova, Savas; Elibol, Birsen; Bulut, Huri; Meral, Ismail; Sahin, Gulderen (NCI CPTAC, 2021)

In this study, we investigated the protective effects of angiotensin IV (Ang IV) on cognitive function in streptozotocin (STZ)‑induced diabetic rats. Male Wistar albino rats, were randomly divided into four groups; control ...

The healing effects of the topical mesenchymal stem cell application on colonic anastomosis subjected to ischemia reperfusion injury

Ozden, Huseyin; Karaca, Gokhan; Bulut, Huri; Niyaz, Mehmet; Gomec, Muhammed; Daphan, Cagatay E. (KAFKAS UNIV, 2021)

Intestinal ischemia reperfusion injury (IRI) is a challenging problem and it adversely affects the healing of colonic anastomosis. Our experimental study aimed to investigate the role of mesenchymal stem cells (MSC) ...

Cuscuta campestris tedavisi ile mide kanseri hücrelerinde apoptozun indüklenmesi ve reaktif oksijen türlerinin oluşumu yoluyla proliferasyonun engellenmesi

Bulut, Huri; Durmus, Ezgi; Hacıosmanoglu, Ebru; Bozali, Kubra; Senturk, Hilal; Kocyigit, Abdurrahim (DergiPark, 2021)

Amaç: Kanser tahrip edici, ölümcül bir hastalıktır ve dünya çapındaki ölüm nedenleri arasında ikinci sırada yer almaktadır. Mide kanseri gibi kanser türleri için farklı tedavi yöntemleri mevcut olsa da çoğu tedavi yöntemleri ...

Serum survivin is decreased in women with preeclampsia

Guralp, Onur; Gok, Koray; Tuten, Nevin; Hamzaoglu, Kubra; Makul, Melike; Bulut, Huri (Taylor & Francis Online, 2021)

Objective: To evaluate the serum survivin level in preeclampsia.Methods: Eighty-eight pregnancies complicated with preeclampsia and 88 gestational-age (GA)-matched uncomplicated pregnancies were evaluated.Results: Mean ...