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Comparison of mesenchymal stem cell sheets and chondrocyte sheets in a rabbit growth plate injury model

Gultekin, Alper; Agirdil, Yucel; Duman, Busra Oncel; Subasi Demir, Cansu; Karaoz, Erdal (Tubitak Scientific & Technical Research Council Turkey, 2020)

Background/aim: The treatment of posttraumatic deformities and differences in length between the extremities resulting from physeal injury remains controversial. The aims of this study were to compare the efficacy of ...

Determination of antibiotic impurities in good manufacturing practices-grade cell therapy medicinal products

Oztel, Olga Nehir; Korkmaz, Seval; Karaoz, Erdal (Taylor & Francis Inc, 2020)

Backrounds: According to the regulations of the health autorities, cell-based therapy products must be manufactured in good manufacturing production (GMP) facilities, fulfilling the required GMP standards. Products developed ...

Functional recovery after wharton's jelly-derived mesenchymal stem cell administration in a patient with traumatic brain injury: a pilot study

Kabatas, Serdar; Civelek, Erdinc; Sezen, Gulseli Berivan; Kaplan, Necati; Savrunlu, Eyup Can; Cetin, Ercan; Diren, Furkan; Karaoz, Erdal (TURKISH NEUROSURGICAL SOC, 2020)

AIM: To introduce a traumatic brain injury (TBI) patient who underwent stem cell transplantation (SCT) in order to minimize the remaining injury deficiencies. MATERIAL and METHODS: This study included a 29 years old ...

Can Wharton jelly derived or adipose tissue derived mesenchymal stem cell can be a treatment option for duchenne muscular dystrophy? answers as transcriptomic aspect

Sun Gungorurler, Eda; Karaoz, Erdal (2020)

Introduction: Mesenchymal stem cells (MSCs) are able to differentiate into several cell lineages including skeletal muscle. In addition to their differentiation capacities, they have the ability to transfer their content ...

Mesenchymal stem cells treatment in COVID-19 patient with multi-organ involvement

Yilmaz, R.; Adas, G.; Cukurova, Z.; Yasar, Kart K.; Isiksacan, N.; Oztel, O. N.; Karaoz, Erdal (COMENIUS UNIV, 2020)

The aim of this study is to evaluate the therapeutic effect of mesenchymal stem cells (MSCs) in a severe case of brain and multiple organ involvement in a patient with COVID-19. Here, a 51-year-old male patient with ...

Improving effects of mesenchymal stem cells on symptoms of chronic obstructive pulmonary disease

Karaoz, Erdal; Kalemci, Serdar; Ece, Ferah (Comenius Univ, 2020)

AIM: We aimed to identify the improving effects of umbilical cord tissue-derived (UCTD) MSCs on the symptoms of COPD in our phase 1.2 clinical study. MATERIAL METHODS: Our study consisted of five patients with COPD. ...

Calvarial bone defects in ovariectomised rats treated with mesenchymal stem cells and demineralised freeze-dried bone allografts

Kadiroglu, Ela Tules; Akbalik, Mehmet Erdem; Karaoz, Erdal; Kanay, Berna Ersoz; Dag, Ahmet; Ketani, Muzaffer Aydın; Eroglu, E. G.; Uysal, Ersin; Tuncer, Cudi M. (NLM (Medline), 2020)

BACKGROUND: The aim of the study was to investigate the ability of a combination of bone marrow mesenchymal stem cells (BM-MSCs) with and without demineralised freeze-dried bone allografts (DFDBAs) to induce bone regeneration ...

Cardiovascular changes in WAG/Rij rats with genetic absence epilepsy: effects of chronic ethosuximide treatment

Sahin, Tugce Demirtas; Utkan, Tijen; Karson, Ayse; Yazir, Yusufhan; Karaoz, Erdal (CUKUROVA UNIV, 2020)

Purpose: The aim of this study was to investigate the effects of chronic ethosuximide (ETX) treatment on absence seizures and cardiovascular parameters in WAG/Rij rats with genetic absence epilepsy. Materials and Methods: ...