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Pankreas kanserinde yeni sentezlenen pt(ıı) sakkarinat kompleksi kimyasal bileşiğinin, antikanser etkinliğinin araştırılması
(İstinye Üniversitesi / Sağlık Bilimleri Enstitüsü, 2020)
Pankreas kanseri genellikle hastalığın son evrelerinde belirti veren sinsi bir hastalıktır.
Bununla birlikte günümüzün en ölümcül 4. kanser türü olarak bilinmektedir.
Kemoterapi tedavisi sonrasında hücrelerin kazandığı ...
Yeni sentez platin (II) sakkarinat kompleksinin (trans[PT(sac)2(PPH2CY)2]) panc-1 pankreas kanseri hücreleri üzerindeki sitotoksik/apoptotik etkilerinin araştırılması
(İstinye Üniversitesi / Sağlık Bilimleri Enstitüsü, 2020)
Pankreas kanseri, agresif ve malign özelliği yüksek olan, erken tanısının zor olması
ve hızlı metastaz kabiliyeti ile ölüm oranı yüksek olan bir kanser türüdür. Diğer
kanser türlerinde olduğu gibi pankreas kanserinde de ...
Toxicity assessment of Hypericum olympicum subsp. olympicum L. on human lymphocytes and breast cancer cell lines
(Univ South Bohemia, 2020)
There is a limited number of studies about the constituents of Hypericum olympicum subsp. olympicum and its genotoxic and cytotoxic potency. We examined the possible antigenotoxic/genotoxic properties of methanolic extract ...
Cytotoxic platinum(II) complexes derived from saccharinate and phosphine ligands: synthesis, structures, DNA cleavage, and oxidative stress-induced apoptosis
(Springer, 2020)
A series of the structurally related platinum(II) saccharinate (sac) complexes with alkylphenylphosphines, namely cis-[Pt(sac)(2)(PPh2Me)(2)]center dot DMSO (1), cis-[Pt(sac)(2)(PPhMe2)(2)] (2), cis-[Pt(sac)(2)(PPh2Et)(2)] ...
Trans-Pd/Pt(II) saccharinate complexes with a phosphine ligand: Synthesis, cytotoxicity and structure-activity relationship
(Pergamon-Elsevier Science Ltd, 2020)
New trans-[Pd(sac)(2)(PPhMe2)(DMSO)]center dot H2O (Pd) and trans-[Pt(sac)(2)(PPhMe2)(2)]center dot H2O (Pt) complexes (sac = saccharinate and PPhMe 2 = dimethylphenylphosphine) were synthesized and characterized by elemental ...
Highly promising antitumor agent of a novel Platinum(II) complex bearing a tetradentate chelating ligand
(Amer Chemical Soc, 2020)
A new mononuclear cationic platinum(II) coordination compound with 6,6'-bis(NH-benzimidazol-2-yl)-2,2'-bipyridine (L) ligand having N-4-tetradentate binding pocket [Pt(L)]-Cl-2.2H(2)O (Complex 1) was synthesized and ...
Mixed ligand complexes of Co(II), Ni(II) and Cu(II) with quercetin and diimine ligands: synthesis, characterization, anti-cancer and anti-oxidant activity
(Springer, 2020)
In this work, mixed ligand complexes of Co(II) Ni(II) and Cu(II) were synthesized using quercetin and diimine (1,10-phenanthroline or 2,2 '-bipyiridine) ligands. The obtained Ni(II) and Co(II) complexes are new and the ...
Synthesis, FT-IR and NMR characterization, antimicrobial activity, cytotoxicity and DNA docking analysis of a new anthraquinone derivate compound
(Taylor & Francis Inc, 2020)
A new anthraquinone [1-(2-Aminoethyl)piperazinyl-9,10-dioxo-anthraquinone] derivative was synthesized and characterized by density functional theory (DFT) calculations, experimental and theoretical vibrational spectroscopy ...
