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Naftakinon türevli yeni sentez bileşiklerin kanser hücre hatları üzerine etkisinin incelenmesi
(İstinye Üniversitesi / Sağlık Bilimleri Enstitüsü, 2020)
Prostat kanseri dünyada ikinci, İskandinavya da dahil gelişmiş ülkelerde ise en sık rastlanan birinci kanser türüdür. Hormon ve/veya kemoterapi tedavisi sonrası hücrelerde meydana gelen direnç kanser kaynaklı ölümlerin ...
A novel 1,4-naphthoquinone-derived compound induces apoptotic cell death in breast cancer cells
(TR- Dizin, 2019)
Abstract: Breast cancer is the most-diagnosed cancer type among women. The triple-negative subtype is an especially aggressive type of breast cancer. Although chemotherapy is almost the only option for the treatment of ...
Highly promising antitumor agent of a novel Platinum(II) complex bearing a tetradentate chelating ligand
(Amer Chemical Soc, 2020)
A new mononuclear cationic platinum(II) coordination compound with 6,6'-bis(NH-benzimidazol-2-yl)-2,2'-bipyridine (L) ligand having N-4-tetradentate binding pocket [Pt(L)]-Cl-2.2H(2)O (Complex 1) was synthesized and ...
A promising therapeutic combination for metastatic prostate cancer: Chloroquine as autophagy inhibitor and palladium(II) barbiturate complex
(Elsevier B.V., 2020)
Autophagy is a catabolic process for cells that can provide energy sources and allows cancer cells to evade cell death. Therefore, studies on the combination of autophagy inhibitors with drugs are increasing as a new ...