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Naftakinon türevli yeni sentez bileşiklerin kanser hücre hatları üzerine etkisinin incelenmesi 

Akar, Remzi Okan (İstinye Üniversitesi / Sağlık Bilimleri Enstitüsü, 2020)
Prostat kanseri dünyada ikinci, İskandinavya da dahil gelişmiş ülkelerde ise en sık rastlanan birinci kanser türüdür. Hormon ve/veya kemoterapi tedavisi sonrası hücrelerde meydana gelen direnç kanser kaynaklı ölümlerin ...
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A novel 1,4-naphthoquinone-derived compound induces apoptotic cell death in breast cancer cells 

Karakaş, Didem; Akar, Remzi Okan; Gökmen, Zeliha; Ulukaya, Engin; Deniz, Nahide Gülsah (TR- Dizin, 2019)
Abstract: Breast cancer is the most-diagnosed cancer type among women. The triple-negative subtype is an especially aggressive type of breast cancer. Although chemotherapy is almost the only option for the treatment of ...
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Highly promising antitumor agent of a novel Platinum(II) complex bearing a tetradentate chelating ligand 

Yılmaz, İsmail; Akar, Remzi Okan; Erkısa Genel, Merve; Selvi, Selin; Şengül, Abdurrahman; Ulukaya, Engin (Amer Chemical Soc, 2020)
A new mononuclear cationic platinum(II) coordination compound with 6,6'-bis(NH-benzimidazol-2-yl)-2,2'-bipyridine (L) ligand having N-4-tetradentate binding pocket [Pt(L)]-Cl-2.2H(2)O (Complex 1) was synthesized and ...
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A promising therapeutic combination for metastatic prostate cancer: Chloroquine as autophagy inhibitor and palladium(II) barbiturate complex 

Erkısa Genel, Merve; Aydınlık, Şeyma; Cevatemre, Buse; Aztopal, Nazlıhan; Akar, Remzi Okan; Çelikler, Serap; Yılmaz, Veysel Turan; Ari, Ferda; Ulukaya, Engin (Elsevier B.V., 2020)
Autophagy is a catabolic process for cells that can provide energy sources and allows cancer cells to evade cell death. Therefore, studies on the combination of autophagy inhibitors with drugs are increasing as a new ...



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Akar, Remzi Okan (4)
Ulukaya, Engin (3)Erkısa Genel, Merve (2)Ari, Ferda (1)Aydınlık, Şeyma (1)Aztopal, Nazlıhan (1)Cevatemre, Buse (1)Deniz, Nahide Gülsah (1)Gökmen, Zeliha (1)Karakaş, Didem (1)... View MoreSubject
Apoptosis (4)
Cytotoxicity (2)1,4-naphthoquinones (1)Anti-cancer Drug (1)Anti-kanser İlaç (1)Anticancer Agent (1)Apoptoz (1)Autophagy (1)Benzimidazole (1)Dna Damage (1)... View MoreDate Issued2020 (3)2019 (1)Full Text StatusWith Full Text (4)

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