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Effects of intrathecai verapamil on cerebral vasospasm in experimental rat study

Akkaya, Enes; Evran, Sevket; Calis, Fatih; Cevik, Serdar; Hanimoglu, Hakan; Seyithanoglu, Mehmet Hakan; Katar, Salim; Karatas, Ersin; Kocyigit, Abdurrahim; Saglam, Mustafa Yasin; Hatiboglu, Mustafa Aziz; Kaynar, Mehmet Yasar (Elsevier Science Inc, 2019)

BACKGROUND: Verapamil a calcinarn channel blacker, has shown promising results on cerebral vasospasm. However, it has not yet been accepted for treatment or prevention purposes because of the associated side effects, ...

Targeting AMPK signaling in ischemic/reperfusion injury: From molecular mechanism to pharmacological interventions

Paskeh, Mahshid Deldar Abad; Asadi, Ava; Mirzaei, Sepideh; Hashemi, Mehrdad; Entezari, Maliheh; Raesi, Rasoul; Hushmandi, Kiavash; Zarrabi, Ali; Ertas, Yavuz Nuri; Aref, Amir Reza; Samarghandian, Saeed; Reiter, Russel J; Ren, Jun (2022)

Ischemia is a pathological process in which blood supply to a particular organ is temporarily interrupted resulting in disturbed biological function and homeostasis of local tissues. Following ischemia, reperfusion and ...

A focusing study on radioprotective and antioxidant effects of Annona muricata leaf extract in the circulation and liver tissue: clinical and experimental studies

Elmas, Ozlem; Sahin, Havva Hande Keser; Guven, Berrak; Abuzaid, Mohamed M.; Elshami, Wiam; Almisned, Ghada; Zakaly, Hesham M. H.; Ene, Antoaneta; Tekin, Huseyin Ozan (De Gruyter Open Ltd, 2022)

Objectives: This study investigates the effect of Annona muricata (AM) leaf extract against irradiation-induced damage by the evaluation of hepatic tissue and the levels of oxidative and inflammatory stress in the circulation. ...

Clinical comprehensive and experimental assessment of the radioprotective effect of Annona muricata leaf extract to prevent cellular damage in the ileum tissue

Elmas, Ozlem; Sahin, Havva Hande Keser; Keskin, Emrah; Guven, Berrak; Uslu Erdemir, Rabiye; Almisned, Ghada; Zakaly, Hesham M. H.; Ene, Antoaneta; Tekin, Huseyin Ozan (De Gruyter Open Ltd, 2022)

We report the radioprotective attitude of Annona muricata (AM) leaf extract as antioxidant material to prevent cellular damage in the ileum tissue. The protective effects of an ethyl acetate extract of AM leaves are ...

Unfolded Protein Response is Involved in Trans-Platinum (II) Complex-Induced Apoptosis in Prostate Cancer Cells via ROS Accumulation

Karakaş Zeybek, Didem; Cevatemre, Buse; Oral, Arzu Y.; Yılmaz, Veysel T.; Ulukaya, Engin (Bentham Science Publ Ltd, 2019)

Background: Prostate cancer is one of the most common cancer types and it is the sixth leading cause of cancer-related death in men worldwide. Even though novel treatment modalities have been developed, it still a ...