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Mechanisms of abemaciclib, a CDK4/6 inhibitor, induced apoptotic cell death in prostate cancer cells in vitro

Güney Eskiler, Gamze; Deveci Özkan, Asuman; Hacıefendi, Ayten; Bilir, Cemil (Elsevier, 2022)

The therapeutic effects of abemaciclib (ABE), an inhibitor of cyclin- dependent kinases (CDK) 4/6, on the proliferation of two types of prostate cancer (PC) cells were revealed. In this study, in vitro cytotoxic and apoptotic ...