Secukinumab in a patient with sarcoidosis
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CitationKobak, S., Gungen, A. C., Gungen, B. D., Tutpinar, Y., & Guler, M. (2020). Secukinumab in a patient with sarcoidosis. Scandinavian Journal of Rheumatology, 1-2.
Sarcoidosis is a systemic granulomatous disease, characterized by non-caseating granuloma formation. It usually involves the lungs, but may also affect the eyes, heart, skin, and musculoskeletal system. The pathogenesis is not well known, but it is generally accepted as Th1 disease. The role of Th17-induced cytokines in the development of sarcoid granuloma has been reported.