Atypical variants of takotsubo cardiomyopathy: mechanistic and clinical implications

Abstract

Over past decades, takotsubo cardiomyopathy (TTC) has drawn a substantial interest as a unique form of acute and reversible cardiomyopathy that usually emerges in response to adrenergic hyperactivation associated with a variety of emotional and physical triggers.[1,2] Even though, this phenomenon is generally characterized by an apical balloning pattern (classical variant), it might occasionally present with atypical morphological variants including mid-ventricular, inverted and focal forms of myocardial involvement.