• Haplotypes rich in activating killer-cell immnuglobulin-like receptor genes are associated with delay on age of myeloma onset 

  Akin, Hasan Yalim; Seval, Guldane Cengiz; Atilla, Pinar Ataca; Yurdakul Mesutoglu, Pinar; Otlu, Taner; Anliacik, Ridvan; Dalva, Klara; Gurman, Gunhan; Beksac, Meral (CIG MEDIA GROUP, 2021)

  Natural killer (NK) cells are known for their anti-tumoral cytotoxic effects. Effector NK-cell functions are controlled by interactions between inhibitory and activating killer-cell immnuglobulin-like ...

• The effect of cerebellar transcranial direct current stimulation on balance tests in healthy young 

  Erdogan, Ezgi; Kir, Can; Beycan, Esin; Karakaya, Esin; Altincinar, Sanem; Bayramoglu, Turku; Eskikurt, Gokcer; Karamursel, Sacit (Science Direct, 2019)

  Transcranial direct current stimulation (tDCS) studies showed positive results about postural control and motor adaptation especially in patients and older adults. We aimed to investigate the effect of cerebellar anodal ...

• Generation of induced pluripotent stem cells from human bone marrow-derived mesenchymal stem cells 

  Koyuncu Irmak, Duygu; Karaoz, Erdal (Springer Link, 2021)

  Adult somatic cells can be reprogrammed and become pluripotent called induced pluripotent stem cells (iPSC) when they are induced by the stemness genes. The iPSCs have been representing a research and development platform ...

• Comparison of the effects of intratubal injection of adipose-derived mesenchymal stem cells in a rat sciatic nerve transection: an experimental study 

  Karakol, Percin; Kapı, Emin; Karaoz, Erdal; Tunik, Selcuk; Bozkurt, Mehmet (Wolters Kluwer, 2021)

  This study was designed to evaluate the efficacy of epineural tubulization (ENT) with or without intratubal application of adipose-derived mesenchymal stem cells (ASCs) in the rat model of sciatic nerve transection. After ...

• Investigation of the efficacy of paclitaxel on some miRNAs profiles in breast cancer stem cells 

  Erturk, Elif; Ari, Ferda; Akgun, Oguzhan; Ulukaya, Engin; Kucukali, Cem Ismail; Zeybek, Umit (TUBITAK SCIENTIFIC & TECHNICAL RESEARCH COUNCIL TURKEY, 2021)

  Understanding of the functions of microRNAs in breast cancer and breast cancer stem cells have been a hope for the development of new molecular targeted therapies. Here, it is aimed to investigate the differences in the ...

• Layered double hydroxide-based nanocomposite scaffolds in tissue engineering applications 

  Izbudak, Burcin; Cecen, Berivan; Anaya, İngrid; Kamal Miri, Amir; Bal-Ozturk Ayca; Karaoz, Erdal (Royal Society of Chemistry, 2021)

  Layered double hydroxides (LDHs), when incorporated into biomaterials, provide a tunable composition, controllable particle size, anion exchange capacity, pH-sensitive solubility, high-drug loading efficiency, efficient ...

• Characterization of Covid-19 infected pregnant women sera using laboratory indexes, vibrational spectroscopy, and machine learning classifications 

  Guleken, Zozan; Jakubczyk, Paweł; Paja, W.; Krzysztof, Pancerz; Bulut, Huri; Öten, Esra; Depciuch, Joanna; Tarhan, Nevzat K. (Elsevier B.V., 2022)

  Herein, we show differences in blood serum of asymptomatic and symptomatic pregnant women infected with COVID-19 and correlate them with laboratory indexes, ATR FTIR and multivariate machine learning methods. We collected ...

• The healing effects of the topical mesenchymal stem cell application on colonic anastomosis subjected to ischemia reperfusion injury 

  Ozden, Huseyin; Karaca, Gokhan; Bulut, Huri; Niyaz, Mehmet; Gomec, Muhammed; Daphan, Cagatay E. (KAFKAS UNIV, 2021)

  Intestinal ischemia reperfusion injury (IRI) is a challenging problem and it adversely affects the healing of colonic anastomosis. Our experimental study aimed to investigate the role of mesenchymal stem cells (MSC) ...

• First report of t(1;15)(q21;q11.2) and t(1;21)(q21;q11.2) anomalies in Burkitt Lymphoma 

  Bozkurt, Sureyya; Okay, Mufide; Haznedaroglu, Celalettin Ibrahim (KUWAIT MEDICAL ASSOC, 2021)

  Burkitt lymphoma (BL) is a highly aggressive B cell neoplasm characterized by t(8;14)(q24;q32) which involves the MYC gene. Sometimes, patients have additional cytogenetic anomalies beside t(8;14)(q24;q32) and these anomalies ...

• A rare case report: bilateral occipital artery arising from the vertebral artery 

  Demirbas, Ahmet Taha; Demirtas, Ismet; Sonmez Topcu, Feyza; Karasu, Sevilay; Ayyildiz, Behcet (Springer Nature, 2021)

  Background Variations of the origin of the occipital artery (OA) can be considered as congenital anomalies that are often asymptomatic and detected incidentally on angiography or during cadaver dissection. While OA ...

• Performing the comparative analysis to understand the functional roles of genes in different pathways of cardiomyopathy disease 

  Atak, Evren; Karaoglu, Dilara; Sertturk, Seda; Koyuncu Irmak, Duygu; Yenenler-Kutlu, Asli (Elsevier, 2021)

  Personalized medicine is one of the popular approaches in biological sciences. Due to the great attention in personalized medicine, there exists a need for health decision algorithms developed through high-level ...

• Cuscuta campestris tedavisi ile mide kanseri hücrelerinde apoptozun indüklenmesi ve reaktif oksijen türlerinin oluşumu yoluyla proliferasyonun engellenmesi 

  Bulut, Huri; Durmus, Ezgi; Hacıosmanoglu, Ebru; Bozali, Kubra; Senturk, Hilal; Kocyigit, Abdurrahim (DergiPark, 2021)

  Amaç: Kanser tahrip edici, ölümcül bir hastalıktır ve dünya çapındaki ölüm nedenleri arasında ikinci sırada yer almaktadır. Mide kanseri gibi kanser türleri için farklı tedavi yöntemleri mevcut olsa da çoğu tedavi yöntemleri ...

• A low direct electrical signal attenuates oxidative stress and inflammation in septic rats 

  Ustunova, Savas; Haciosmanoglu, Ebru; Bulut, Huri; Elibol, Birsen; Kilic, Aysu; Hekimoglu, Rumeysa (PMC, 2021)

  Electrical stimulation is proposed to exert an antimicrobial effect according to studies performed using bacterial and cell cultures. Therefore, we investigated the effects of electrification on inflammation in septic rats. ...

• Preparation and characterization of palladium derivate-loaded micelle formulation in vitro as an innovative therapy option against non-small cell lung cancer cells 

  Erkisa, Merve; Ari, Ferda; Buyukkoroglu, Gulay; Senel, Bedriye; Yilmaz, Veysel Turan; Ulukaya, Engin (WILEY, 2021)

  Nanoparticles have been used in cancer treatments to target tumor and reduce side effects. In this study, we aimed to increase the effectiveness of palladium(II) complex [PdCl(terpy)](sac)·2H2O, which previously showed ...

• Diagnosis of endometriosis using endometrioma volume and vibrational spectroscopy with multivariate methods as a noninvasive method 

  Guleken, Zozan; Bulut, Huri; Depciuch, Joanna; Tarhan, Nevzat (Elsevier Science, 2022)

  Endometriomas are typically an advanced form of endometriosis that leads to the formation of scar tissue, adhesions, and an inflammatory reaction. There is no certain serum marker for the diagnosis of endometriosis. This ...

• Water-soluble silver(I) complexes with N-donor benzimidazole ligands containing an imidazolium core: stability and preliminary biological studies 

  Karatas, Mert Olgun; Ozdemir, Namik; Sariman, Melda; Gunal, Selami; Ulukaya, Engin; Ozdemir, Ismail (Royal Society of Chemistry, 2021)

  Herein, we report the synthesis, characterisation and preliminary biological evaluation of two novel silver(I) complexes of type [AgL2](NO3)3 (3 and 4) with ionic N-donor benzimidazoles. The complexes have been synthesized ...

• Palladium (II) complex and thalidomide intercept angiogenic signaling via targeting FAK/Src and Erk/Akt/PLC gamma dependent autophagy pathways in human umbilical vein endothelial cells 

  Aydinlik, Seyma; Uvez, Ayca; Kiyan, Hulya Tuba; Gurel-Gurevin, Ebru; Yilmaz, Veysel Turan; Ulukaya, Engin (Elsevier, 2021)

  The current study assessed the effects of the thalidomide and palladium (II) saccharinate complex of terpyridine on the suppression of angiogenesis-mediated cell proliferation. The viability was assessed after treatment ...

• Serum neprilysin levels are elevated in preeclampsia 

  Tüten, Nevin; Malik, Eduard; Gök, Koray; Hamzaoğlu, Kübra; Makul, Melike; Öner, Yahya Özgün; Bulut, Huri; Tüten, Abdullah; Güralp, Onur Şahin (Elsevier Ltd, 2021)

  Objective: To evaluate the possible associations between serum Neprilysin (NEP) levels and preeclampsia and mild and severe preeclampsia subgroups. Materials and methods: Fifty-five consecutive women with mild preeclampsia ...

• Comparison of four phenotypic assays and check-direct CPE for detection of carbapenemases-producing enterobacterales 

  Abulaila, Ayham; Erdem, Fatma; Öncül, Oral; Aktaş, Zerrin (Verlag Klinisches Labor GmbH, 2021)

  Background: Early and accurate detection of carbapenemase-producing Enterobacterales (CPE) is fundamental to prevent their spread in hospital environment. Our objective was to compare between four commonly used phenotypic ...

• Assessment of the effect of endocrine abnormalities on biomacromolecules and lipids by FT-IR and biochemical assays as biomarker of metabolites in early Polycystic ovary syndrome women 

  Guleken, Zozan; Bulut, Huri; Bulut, Berk; Depciuch, Joanna (Elsevier, 2021)

  Polycystic ovary syndrome (PCOS) is a common endocrinopathy associated with metabolic disturbances.Both in the development and improvement of the disease, the structure of phospholipids and proteinsin the blood serum plays ...

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