Temel Tıp Bilimleri Bölümü Makale Koleksiyonu
Recent Submissions
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Differentiation of claustrum resting-state functional connectivity in healthy aging, alzheimer's disease, and parkinson's disease
(John Wiley and Sons Inc, 2022)The claustrum is a sheet-like of telencephalic gray matter structure whose function is poorly understood. The claustrum is considered a multimodal computing network due to its reciprocal connections with almost all cortical ... -
Anti-apoptotic effects of valproic acid treatment on dopaminergic neuronal loss in a 6-hydroxydopamine model of parkinson’s disease in rats
(2022)Aim: Parkinson’s disease (PD) is characterized by the progressive loss of dopaminergic neurons resulting in deterioration of motor activity in patients. Currently, available therapies including Levodopa (L-DOPA) are more ... -
Is adrenomedullin upregulation due to apical periodontitis independent of periodontal disease?
(SPRINGER, 2022)To investigate the relationship between apical periodontitis [AP] severity and inflammatory markers [interleukin (IL)-12, tumor necrosis factor-alpha (TNF-alpha), and Mid-Regional Pro Adrenomedullin (MR-proADM)] in patients ... -
The investigation of the effects of postnatal alcohol exposure on molecular content and antioxidant capacity of mice liver tissue
(PERGAMON-ELSEVIER SCIENCE LTD, 2022)One of the most common causes of fetal alcohol spectrum disease (FASD) characterized with neuro-developmental disorder and growth retardation, is the postnatal alcohol consumption. Since studies in literature are mainly ... -
Single session anodal transcranial direct current stimulation on different cortical areas effects on pain modulation in healthy subjects
(HOGREFE PUBLISHING CORP, 2022)Transcranial direct current stimulation (tDCS) studies in healthy volunteers have shown conflicting results in terms of modulation in pain thresholds. The aim of this study was to investigate how single session anodal tDCS ... -
Morphometric evaluation of second to difth metacarpals for retrograde intramedullary headless screw fixation
(Universidad de la Frontera, 2022)Intramedullary headless screw fixation has come to the fore in the treatment of metacarpal fractures in recent years with its advantages. Our aim was to evaluate the metacarpal morphometry for retrograde intramedullary ... -
The prognostic and predictive values of differential expression of exosomal receptor tyrosine kinases and associated with the PI3K/AKT/mTOR signaling in breast cancer patients undergoing neoadjuvant chemotherapy
(Springer Science and Business Media Deutschland GmbH, 2022)Purpose: Cancer cell-derived exosomes are the mediator of the tumor microenvironment and the molecular content of exosomes presents a promising prognostic or predictive marker in tumor progression and the treatment response ... -
Time kill-assays of antibiotic combinations for multidrug resistant clinical isolates of OXA-48 carbapenemase producing Klebsiella pneumoniae
(AkJournals, 2022)Treatment of infections caused by OXA-48 carbapenemase producing multidrug-resistant isolates often necessitates combination therapy. In vitro effect of different antibiotic combinations against multidrug-resistant (MDR) ... -
Geometric morphometric study of anterior branches of external carotid artery and carotid bifurcation by 3D-CT angiography
(Springer, 2022)Purpose The aim of our study was to determine the variations of the anterior branches of the external carotid artery (ECA) and investigate the morphometric and geometric features of the anterior branches of the ECA and ... -
Manual versus automated volume reduction of cord blood
(TR- Dizin, 2022)Objectives: All cord blood banks all over the world follow a common procedure, concentrating progenitor cells by volume reduction, with the main purpose of optimizing the use of storage space. The main objective of this ... -
Aberrant activation-induced cytidine deaminase gene expression links BCR/ABL1-negative classical myeloproliferative neoplasms
(TR- Dizin, 2022)Aim: Activation-induced cytidine deaminase (AID) has been associated with tumor initiation and development because of its ability to generate DNA damage and somatic mutations that cause genomic instability. This study ... -
The effect of omentectomy on the blood levels of adipokines in obese patients with endometrial cancer
(Elsevier Science, 2022)Objective To investigate the blood levels of adipokines in obese patients with endometrial cancer who have and have not undergone omentectomy. Methods Between September 2017 and September 2019, the study recruited 54 ... -
The improved killing of both androgen-dependent and independent prostate cancer cells by etoposide loaded SPIONs coupled with NIR irradiation
(Royal Society of Chemistry, 2022)Etoposide (Eto) is a toxic drug that shows promise in treating prostate cancer (PCa) but confers significant side effects, and has poor solubility and bioavailability. Nanoparticles are quite successful in overcoming such ... -
Serum neutrophil gelatinase-associated lipocalin concentrations are significantly associated with the severity of COVID-19 in pregnant patients
(Saudimedj, 2022)Objectives: To evaluate serum neutrophil gelatinaseassociated lipocalin (NGAL) concentrations of pregnant women complicated with coronavirus disease 2019 (COVID-19) and investigate its diagnostic value for the severity ... -
A novel 1,4-naphthoquinone-derived compound induces apoptotic cell death in breast cancer cells
(TR- Dizin, 2019)Abstract: Breast cancer is the most-diagnosed cancer type among women. The triple-negative subtype is an especially aggressive type of breast cancer. Although chemotherapy is almost the only option for the treatment of ... -
Distance education during social isolation: an evaluation of student attitudes and perceptions using the web-based learning environment instrument (WEBLEI)
(DergiPark, 2021)Objectives: Until recently, distance education at universities has supplemented face-to-face education in blended programs that combine the two. But during the COVID-19 pandemic in the spring of the 2019–2020 academic ... -
İnsanı geliştirme tartışmalarına biyoetik bir bakış
(TR- Dizin, 2020)Uygulamalı etiğin önemli dallarından biri olan tıp etiği, özellikle yeni tıbbi tedavi yöntem ve teknolojilerinin İnsanlar üzerinde denenmesiyle günümüz felsefi tartışmalarında daha çok yer almaya başlamıştır. Biyoetik ... -
Can ankle-brachial index be used as a predictor for carotid artery shunt application during carotid endarterectomy?
(TR- Dizin, 2021)Objectives: This study aims to investigate the possible relationship between low ankle-brachial index (ABI) and shunt requirement during carotid endarterectomy (CEA) operations. Patients and methods: Medical records of ... -
Biophysical overview of Covid-19 infection
(TR- Dizin, 2021)Şiddetli akut solunum sendromu koronavirüs 2 (SARS-CoV-2) enfeksiyonu, 11 Mart 2020 tarihinde DSÖ tarafından küresel bir pandemi ilan edilmiştir. Koronavirüs hastalığı (COVID-19), SARS-CoV-2’nin neden olduğu bulaşıcı ... -
Combinations of wharton Jelly derived exosomes and salicylic acid: A new hope for eradication of cutaneous leishmaniasis
(PARLAR SCIENTIFIC PUBLICATIONS, 2022)The aim of the current study is to obtain wharton jelly derived exosomes, prepare therapeutic formulations including combinations of isolated exosomes and salicylic acid, investigate their in vitro antileishmanial activities ...