• Phase I study on the safety and preliminary efficacy of allogeneic mesenchymal stem cells in hypoxic-ischemic encephalopathy 

  Kabatas, Serdar; Civelek, Erdinç; Kaplan, Necati; Savrunlu, Eyüp Can; Sezen, Gülseli Berivan; Chasan, Mourat; Can, Halil; Genç, Ali; Akyuva, Yener; Boyalı, Osman; Diren, Furkan; Karaoz, Erdal (Baishideng Publishing Group Co, 2021)

  BACKGROUND Hypoxic-ischemic encephalopathy (HIE) is a leading cause of morbidity and mortality in the adult as well as in the neonate, with limited options for treatment and significant dysfunctionality. AIM To investigate ...

• Effects of Melatonin and Memantine Administration on The Learning and Memory Performances of Hypoxic Juvenile Rat Pups 

  Elibol, Birsen; Sahbaz, Cigdem; Eyuboglu, Signem; Cevreli, Burcu; Kilic, Ulkan; Kilic, Ertugrul (YERKURE TANITIM & YAYINCILIK HIZMETLERI A S, 2020)

  Objective: Herein, we aimed to investigate the long-term effects of neonatal hypoxia and the potential protective role of melatonin and memantine on the learning and memory. Methods: Seven-day-old rat underwent right ...

• Assessment of structural protein expression by FTIR and biochemical assays as biomarkers of metabolites response in gastric and colon cancer 

  Guleken, Zozan; Bulut, Huri; Gültekin, Güldal İnal; Arikan, Soykan; Yaylim, Ilhan; Hakan, Mehmet Tolgahan; Sönmez, Dilara; Tarhan, Nevzat K.; Depciuch, Joanna (Elsevier B.V., 2021)

  Colon and gastric cancers are the widespread benign types of cancers which are synchronous and metachronous neoplasms. In terms of the progression and progress of the disease, metabolic processes and differentiation in ...

• The effect of direct electric current on motion behaviour in a transgenic beta-amyloid model of caneorhabditis elegans: an In-vivo study 

  Destanoglu, Leyla; Oter, Berre; Tengirsek, Emircan; Yalcin, Tuncer; Bilgin, Sevim; Nafisi, Sara; Karis, Denizhan; Olgun, Abdullah (KARGER, 2021)

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• High-fat diet enhances gastric contractility, but abolishes nesfatin-1-induced inhibition of gastric emptying 

  Ozdemir-Kumral, Zarife N.; Koyuncuoglu, Turkan; Arabaci-Tamer, Sevil; Cilingir-Kaya, Ozlem T.; K. Koroglu, Ayca; Yuksel, Meral; C. Yegen, Berrak (2021)

  Background/Aims Gastrointestinal motility changes contribute to development and maintenance of obesity. Nesfatin-1 (NES-1) is involved in central appetite control. The aim is to elucidate effects of NES-1 and high-fat ...

• Generation of induced pluripotent stem cells from patients with multiple myeloma 

  Yilmaz Basaran, Irem; Karaoz, Erdal (gelenos, 2021)

  Yamanaka and Takahashi made a discovery in the world of life science by transforming mouse somatic fibroblasts into pluripotent cells as a result of transferring 4 gene sets (Sox2-Oct4- Klf4&c-Myc) in 2006 (1). Since ...

• Antibodies against EGF-like domains in Ixodes scapularis BM86 orthologs impact tick feeding and survival of Borrelia burgdorferi 

  Koči, Juraj; Bista, Sandhya; Chirania, Payal; Yang, Xiuli; Kitsou, Chrysoula; Buyuktanir Yas, Ozlem (Nature Publishing Group, 2021)

  Ixodes scapularis ticks transmit multiple pathogens, including Borrelia burgdorferi sensu stricto, and encode many proteins harboring epidermal growth factor (EGF)-like domains. We show that I. scapularis produces multiple ...

• SDF-1 modulates periodontal ligament-Mesenchymal Stem Cells (pdl-MSCs) 

  Hakki, Sema S.; Bozkurt, Buket S; Hakki, Erdogan E.; Karaoz, Erdal; Unlu, Ali; Kayis, Seyit Ali (WILEY, 2021)

  Background/objectives: In this in vitro study, the effects of Stromal cell-derived factor-1 (SDF-1) was evaluated on the periodontal ligament-Mesenchymal Stem Cells (pdl-MSCs) functions. Material and methods: Real-time ...

• Spectrochemical and biochemical assay comparison study of the healing effect of the aloe vera and hypericum perforatum loaded nanofiber dressings on diabetic wound 

  Guleken, Zozan; Depciuch, Joanna; Ege, Hasan; Ilbay, Gul; Kalkandelen, Cevriye; Ozbeyli, Dilek; Bulut, Huri; Tarhan, Nevzat; Erdem Kuruca, Serap (Elsevier, 2021)

  Diabetic wounds have a slow healing process and easy to be infected. In addition to current drug treatments, supportive approaches are needed for diabetic wound treatment. In this study, we aimed to load Aloe Vera (AV) and ...

• Endogenous retrovirus HERV-K6 and HERV-K11 polymorphisms’ analyses in head and neck squamous cell carcinoma patients 

  Karlik, Elif; Gurbuz, Orkun; Yildiz, Yemliha; Gozukirmizi, Nermin (Elsevier B.V., 2021)

  Many tumors, such as melanoma, breast cancer, germ cell tumors, renal cancer or ovarian cancer, express HERV proteins, mainly HERV-K (HML6) and HERV-K (HML2). However, there is no report showing any relation between squamous ...

• Effects of TNF inhibitors and an IL12/23 inhibitor on changes in body weight and adipokine levels in psoriasis patients: a 48-week comparative study 

  Onsun, Nahide; Akaslan, Tahsin Cagdas; Sallahoglu, Kadriye; Gulcan, Aliye Sevdem; Bulut, Huri; Yabaci, Aysegul (Taylor and Francis, 2021)

  Background: Psoriasis is a chronic inflammatory disease associated with obesity and metabolic syndrome. Adipokines are thought to be a link between psoriasis and obesity. Leptin, adiponectin, and omentin are bioactive ...

• Olfactory ensheathing cells: unique glial cells promising for treatments of spinal cord injury 

  Ursavas, Selin; Darici, Hakan; Karaoz, Erdal (Wiley, 2021)

  Spinal cord injury (SCI) is generally the consequence of physical damage, which may result in devastating consequences such as paraplegia or paralysis. Some certain candidates for SCI repair are olfactory ensheathing cells ...

• Epigenetic modulators combination with chemotherapy in breast cancer cells 

  Ari, Ferda; Napieralski, Rudolf; Akgun, Oguzhan; Magdolen, Viktor; Ulukaya, Engin (Wiley, 2021)

  Despite the concerning adverse effects on tumour development, epigenetic drugsare very promising in cancer treatment. The aim of this study was to compare the dif-ferential effects of standard chemotherapy regimens (FEC: ...

• Does inflammation play a pole in the pathophysiology of tinnitus? 

  Demir, Meltem (2021)

  Objective: The present study aimed to investigate the potential of neutrophil/ lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR) and mean platelet volume (MPV) as prognostic markers in tinnitus patients at inflammatory ...

• Sosyal izolasyon döneminde uzaktan öğretim modelinin tıp fakültesi öğrencileri üzerindeki etkilerinin değerlendirilmesi 

  Demirtas, Ismet; Ayyildiz, Sevilay; Ayyildiz, Behcet; Kus, Koral Caglar (DergiPark, 2020)

  Amaç: Covid-19 pandemisi süresince verilen uzaktan tıp eğitiminin, öğrenciler üzerindeki etkilerinin nitel ve nicel yansımaları ile birlikte değerlendirilmesi amaçlandı. Gereç ve Yöntem: Çalışma 217 tıp fakültesi öğrencisi ...

• Evaluation of neurological examination, sep results, mri results, and lesion levels in patients who had been operated for myelomeningocele 

  Canaz, Gokhan; Canaz, Huseyin; Tuna Erdogan, Ezgi; Alatas, Ibrahim; Emel, Erhan; Matur, Zeliha (Wolters Kluwer Medknow Publications, 2020)

  Objective: Myelomeningocele is the most severe and the most frequent form of spina bifida. Most of the myelomeningocele patients undergo operations in newborn age. In terms of life quality and rehabilitation, follow-up's ...

• Meme kanserli hastalarda ABCG2 G34A gen polimorfizminin incelenmesi 

  Yildiz, Yemliha; Arikan, Soykan; Candan, Gonca; Turan, Saime; Yaylim, Ilhan; Ergen, Arzu (DergiPark, 2017)

  ABCG2 plazma membranında yerleşmiş olan bir yarım ATP- bağlı kaset taşıyıcıdır. Enerji bağımlı bir akış pompası ve taşıyıcı olarak, toksik bileşikler ve antikanser ilaçların da olduğu, geniş aralıktaki yapısal olarak ...

• Anatomical differences of variant intracranial cysts 

  Colak, Tuncay; Bamac, Belgin; Erdogan, Mehtap; Orha, Ayla Tekin; Acar, Derya; Ozbek, Aydin (NIGERIAN MEDICAL ASSOC, 2020)

  Cavum vergae, cavum septum pellucidum and cavum veli interpositi are brain midline embryological developmental cysts. They are rarely seen after trauma. Generally, they do not constitute clinical findings. These cysts ...

• Lösemi modelinde tüm Genom RNA dizileme analiz algoritması geliştirilmesi 

  Sun Gungorurler, Eda; Sayitoglu, Muge (DergiPark, 2020)

  Amaç: RNA Dizileme teknolojisi gen anlatım farklılıkları ve kodlayan bölgedeki varyasyonlar, kodlama yapmayan küçük RNAların anlatımları ve gen füzyonlarının belirlenmesi ile bu farklılıkların nedenlerini sunabilmektedir. ...

• A case mimicking chronic myeloid leukemia with t(8;22)(p11;q11)/BCR-FGFR1 and sequential transformation to B-acute lymphoblastic leukemia and acute myeloid leukemia 

  Bayrak, Ayse Gul; Ucur, Ali; Daglar-Aday, Aynur; Bagatır, Gulcin; Erdem, Simge; Hancer, Veysel Sabri; Nalcacı, Meliha; Ozturk, Sukru; Cefle, Kivanc; Palanduz, Sukru; Yavuz, Akif Selim (Springer Science and Business Media Deutschland GmbH, 2021)

  Myeloid/lymphoid neoplasm is a rare malignancy with an aggressive course and rapid transformation to acute myeloid leukemia (AML), or less frequently to acute lymphoblastic leukemia (ALL). Cases with t(8;22)(p11;q11) ...

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