Changes in antimicrobial resistance and outcomes of health care-associated infections
Elmaslar Mert, Habibe Tulin
Karakoc, Zehra Cagla
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CitationAydın, M., Azak, E., Bilgin, H., Menekse, S., Asan, A., Mert, H., Yulugkural, Z., Altunal, L. N., Hatipoğlu, Ç. A., Tuncer Ertem, G., Altunok, E. S., Demirkaya, M. H., Çeviker, S. A., Akgul, F., Memis, Z., Konya, P., Azap, A., Aydin, G., Korkmaz, D., Karakoç, Z. Ç., … Ergönül, Ö. (2021). Changes in antimicrobial resistance and outcomes of health care-associated infections. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 10.1007/s10096-020-04140-y. Advance online publication. https://doi.org/10.1007/s10096-020-04140-y
To describe the change in the epidemiology of health care-associated infections (HAI), resistance and predictors of fatality we conducted a nationwide study in 24 hospitals between 2015 and 2018. The 30-day fatality rate was 22% in 2015 and increased to 25% in 2018. In BSI, a significant increasing trend was observed for Candida and Enterococcus. The highest rate of 30-day fatality was detected among the patients with pneumonia (32%). In pneumonia, Pseudomonas infections increased in 2018. Colistin resistance increased and significantly associated with 30-day fatality in Pseudomonas infections. Among S. aureus methicillin, resistance increased from 31 to 41%.