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dc.contributor.authorAlarçın, Emıne
dc.contributor.authorBal-Öztürk, Ayça
dc.contributor.authorAvcı, Hüseyin
dc.contributor.authorGhorbanpoor, Hamed
dc.contributor.authorGüzel, Fatma Doğan
dc.contributor.authorAkpek, Ali
dc.contributor.authorYesiltas, Gözde
dc.contributor.authorCanak-Ipek, Tuba
dc.contributor.authorAvci-Adali, Meltem
dc.date.accessioned2021-06-08T11:16:46Z
dc.date.available2021-06-08T11:16:46Z
dc.date.issued2021en_US
dc.identifier.citationAlarcin, E., Bal-Öztürk, A., Avci, H., Ghorbanpoor, H., Dogan Guzel, F., Akpek, A., ... & Avci-Adali, M. (2021). Current Strategies for the Regeneration of Skeletal Muscle Tissue. International Journal of Molecular Sciences, 22(11), 5929.en_US
dc.identifier.issn1661-6596
dc.identifier.urihttps://doi.org/10.3390/ijms22115929
dc.identifier.urihttps://hdl.handle.net/20.500.12713/1784
dc.description.abstractTraumatic injuries, tumor resections, and degenerative diseases can damage skeletal muscle and lead to functional impairment and severe disability. Skeletal muscle regeneration is a complex process that depends on various cell types, signaling molecules, architectural cues, and physi-cochemical properties to be successful. To promote muscle repair and regeneration, various strategies for skeletal muscle tissue engineering have been developed in the last decades. However, there is still a high demand for the development of new methods and materials that promote skeletal muscle repair and functional regeneration to bring approaches closer to therapies in the clinic that structurally and functionally repair muscle. The combination of stem cells, biomaterials, and bio-molecules is used to induce skeletal muscle regeneration. In this review, we provide an overview of different cell types used to treat skeletal muscle injury, highlight current strategies in biomaterial-based approaches, the importance of topography for the successful creation of functional striated muscle fibers, and discuss novel methods for muscle regeneration and challenges for their future clinical implementation.en_US
dc.language.isoengen_US
dc.publisherMDPI AGen_US
dc.relation.isversionof10.3390/ijms22115929en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHydrogelsen_US
dc.subjectScaffold Topographiesen_US
dc.subjectSkeletal Muscle Cellsen_US
dc.subjectTissue Engineeringen_US
dc.titleCurrent strategies for the regeneration of skeletal muscle tissueen_US
dc.typereviewen_US
dc.contributor.departmentİstinye Üniversitesi, Eczacılık Fakültesi, Eczacılık Temel Bilimleri Bölümüen_US
dc.contributor.authorID0000-0002-6502-528Xen_US
dc.contributor.institutionauthorBal-Ozturk, Ayca
dc.identifier.volume22en_US
dc.identifier.issue11en_US
dc.relation.journalInternational Journal of Molecular Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.description.wospublicationidWOS:000660171400001en_US
dc.description.pubmedpublicationid34072959en_US
dc.description.wosqualityQ1en_US


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