Browsing WoS İndeksli Yayınlar Koleksiyonu by Department "İstinye Üniversitesi, Eczacılık Fakültesi, Eczacılık Teknolojisi Bölümü"
Now showing items 1-13 of 13
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Applying quality by design approach for the determination of potent paclitaxel loaded poly(lactic acid) based implants for localized tumor drug delivery
(Taylor and Francis, 2022)In the present study, poly(lactic acid) (PLA) and poly(ethylene succinate) (PESu) or poly(ethylene glycol) (PEG) under the framework of quality by design, were blended to produce effective sustained-release matrices for ... -
Basic good manufacturing practices (GMP), special conditions and inspection processes in the covid19 (SARS-CoV-2) pandemic
(Marmara University, 2022)The COVID-19 pandemic has severely impacted the world economy, businesses and global health. Exceptional situations are evident in the food, cosmetics and pharmaceutical production in the supply chain, where many businesses ... -
Current status of mucoadhesive gel systems for buccal drug delivery
(Bentham Science, 2021)Background: Buccal drug delivery is a fascinating research field. Gel-based formulations present potent characteristics as buccal systems since they have great physicochemical properties. Methods: Among the various gels, ... -
Detecting and targeting neurodegenerative disorders using electrospun nanofibrous matrices: current status and applications
(2020)cteristics. Such nanofibrous matrices can be delivered through different administration routes in order to target various diseases. In this review, the most recent advancements in electrospun nanofibrous systems that target ... -
Early effects of low molecular weight heparin therapy with soft-mist inhaler for COVID-19-induced hypoxemia: a phase iib trial
(MDPI, 2021)In COVID-19-induced acute respiratory distress syndrome, the lungs are incapable of filling with sufficient air, leading to hypoxemia that results in high mortality among hospitalized patients. In clinical trials, ... -
Hydrolytic stability of hydroxyphenyl boronic Acids(HPBAs) and employment of Poly(HPBAs) for voltammetric determination of fluoride levels in dental formulations and beverages; Significance of raw DPV Data for chemometric discrimination
(John Wiley and Sons Inc, 2022)Physicochemical and electrochemical properties of hydroxyphenyl boronic acids(HPBAs) and their use in fluoride determinations were investigated. HPBAs were electropolymerized at pH 1.0–11.0 in 40–60 %(v/v) methanol-buffer. ... -
Panvigilance: integrating biomarkers in clinical trials for systems pharmacovigilance
(Mary Ann Liebert, Inc, 2019)Drug safety and pharmacovigilance are rapidly changing with biomarkers and new technologies such as artificial intelligence. However, we need new ideas and application contexts for integration of biomarkers and emerging ... -
Pharmacogenomics for clinical trials of COVID-19 medicines: Why is this important now?
(OMICS, 2021)Historically, pharmacogenomics has origins in biochemical genetics in the 20th century and astute observations on unusual clinical responses to medicines. Extreme drug response phenotypes observed in the clinic have triggered ... -
Preparation and detailed characterization of fusidic acid loaded in situ gel formulations for ophthalmic application
(Marmara University, 2021)This study aimed to assess the potential usage of fusidic acid in situ ocular gels for bacterial conjunctivitis treatment. The in situ gelling systems were applied to improve the bioavailability and residence time of fusidic ... -
Preparation and in vitro-in vivo evaluation of QbD based acemetacin loaded transdermal patch formulations for rheumatic diseases
(Taylor & Francis Ltd, 2022)This research aimed to develop patches for transdermal delivery of acemetacin, which can be used to treat rheumatic diseasesand to determine their potential use. Patches were successfully created by solvent casting method ... -
Pulmonary delivery of favipiravir in rats reaches high local concentrations without causing oxidative lung injury or sSystemic side effects
(MDPI, 2022)Favipiravir displays a rapid viral clearance, a high recovery rate and broad therapeutic safety; however, its oral administration was associated with systemic side effects in susceptible patients. Considering that the ... -
Pulmonary delivery of favipiravir inhalation solution for COVID-19 treatment: in vitro characterization, stability, in vitro cytotoxicity, and antiviral activity using real time cell analysis
(TAYLOR & FRANCIS, 2022)Favipiravir, an RNA-dependent RNA polymerase (RdRp) inhibitor, is used to treat patients infected with influenza virus and most recently with SARS-CoV-2. However, poor accumulation of favipiravir in lung tissue following ... -
An updated review for the diabetic wound healing systems
(Bentham Science, 2021)Background & objective: Diabetes is a global health problem associated with millions of deaths; the most common of diabetes complications is that wounds of diabetic patients tend to heal more slowly or non-healed at all, ...
