Now showing items 1-10 of 48
Wound treatment by stem cells
(SPRINGER INTERNATIONAL PUBLISHING AG, 2017)
Feasibility of allogeneic mesenchymal stem cells in pediatric hypoxic-ischemic encephalopathy: phase I study
(Baishideng Publishing Group Co, 2021)
Background Hypoxic-ischemic encephalopathy (HIE) is one of the leading causes of death and long-term neurological impairment in the pediatric population. Despite a limited number of treatments to cure HIE, stem cell therapies ...
Effects of VEGF plus adipose tissue derived mesenchymal stem cells with platelet rich plasma on inbred rat ovarian functions in premature ovarian insufficiency model
(Oxford Univ Press, 2017)
What is known already: Numerous studies have found an increased risk of congenital malformations among live-born children conceived after assisted reproduction compared with spontaneously conceivedchildren. The underlying ...
Age-related changes in the immunomodulatory effects of human dental pulp derived mesenchymal stem cells on the CD4 + T cell subsets
Mesenchymal stem cells (MSCs) are powerful immunomodulatory cells. The effects of the aging on these abilities of MSCs have not been adequately clarified. In this study, alterations in immunomodulatory abilities of MSCs ...
Safety and efficacy of the stem cell transplantation in friedreich's ataxia: a report of three cases
(IJPHY PUBLISHERS, 2021)
Background: Friedreich's ataxia is a progressive degenerative disorder caused by deficiency of the frataxin protein. Expanded GAA repeats in intron 1 of the FXN gene lead to its heterochromatinization and transcriptional ...
Stem cell based therapy option in COVID-19: is it really promising?
(INT SOC AGING & DISEASE, 2020)
The COVID-19 patients were first detected in China, in December 2019, then the novel virus with associated pneumonia and other diseases spread quickly to worldwide becoming a serious public health intimidation. Despite all ...
Histopathological, immunohistochemical, and biomechanical effects of splenectomy on Achilles tendon healing in rats
(Taylor & Francis Inc, 2019)
Purpose: This study aimed to assess Achilles tendon repair in rats following splenectomy to simulate patients with musculoskeletal system injury who had splenectomy after spleen injury, a situation often seen in orthopedics ...
Olfactory ensheathing cells: unique glial cells promising for treatments of spinal cord injury
Spinal cord injury (SCI) is generally the consequence of physical damage, which may result in devastating consequences such as paraplegia or paralysis. Some certain candidates for SCI repair are olfactory ensheathing cells ...
Isolation, culture, cryopreservation, and preparation of umbilical cord-derived mesenchymal stem cells as a final cellular product under good manufacturing practices-compliant conditions
Mesenchymal stem cells have gained popularity in cell-based therapies due to their regenerative capabilities, immunomodulation properties, and paracrine activity through trophic factors. It is of utmost importance to ...
Isolation, culture, cryopreservation, and preparation of skin-derived fibroblasts as a final cellular product under good manufacturing practice-compliant conditions
Cell-based therapies have become a popular approach in the field of regenerative medicine. Human fibroblast cells, one of the cell types widely used in clinical applications, have been used for skin regeneration and wound ...