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Pearson syndrome in a child transplanted for diamond-blackfan anemia

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Date

2021

Author

Uygun, Vedat
Daloglu, Hayriye
Ozturkmen, Seda
Karasu, Gulsun
Yesilipek, Akif

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Citation

Uygun, V., Daloğlu, H., Öztürkmen, S., Karasu, G., & Yeşilipek, A. (2021). Pearson syndrome in a child transplanted for Diamond-Blackfan anemia. Síndrome de Pearson en un niño trasplantado debido a anemia de Diamond-Blackfan. Archivos argentinos de pediatria, 119(5), e559–e561. https://doi.org/10.5546/aap.2021.eng.e559

Abstract

Pearson syndrome (PS), shares a number of overlapping features with Diamond-Blackfan anemia (DBA), including early onset of severe anemia, making differential diagnosis important. Differential diagnosis of DBA and PS is critical, since those with DBA may respond to treatment with steroids, may undergo remission, or may benefit from hematopoietic stem cell transplantation (HSCT). However, patients with PS have a different prognosis, with a very high risk of developing acidosis, metabolic problems, and pancreatic dysfunction, and a shorter life expectancy than those with DBA. Here we present a patient who underwent HSCT for DBA but was subsequently diagnosed with PS after developing some complications.

Source

Arch Argent Pediatr .

Volume

119

Issue

5

URI

https://doi.org/10.5546/aap.2021.eng.e559
https://hdl.handle.net/20.500.12713/2112

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  • Scopus İndeksli Yayınlar Koleksiyonu [1924]
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