Biyomedikal Mühendisliği Bölümü Makale Koleksiyonu
Recent Submissions
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Fluorescence anisotropy cytosensing of folate receptor positive tumor cells using 3D polyurethane-GO-foams modified with folic acid: molecular dynamics and in vitro studies
(NLM (Medline), 2023)Integrated polyurethane (PU)-based foams modified with PEGylated graphene oxide and folic acid (PU@GO-PEG-FA) were developed with the goal of capturing and detecting tumor cells with precision. The detection of the modified ... -
Superparamagnetic iron oxide nanoparticles and curcumin equally promote neuronal branching morphogenesis in the absence of nerve growth factor in PC12 cells
(MDPI, 2022)Regeneration of the damaged neurons in neurological disorders and returning their activities are two of the main purposes of neuromedicine. Combination use of specific nanoformulations with a therapeutic compound could be ... -
N-doped carbon nanospheres as selective fluorescent probes for mercury detection in contaminated aqueous media: chemistry, fluorescence probing, cell line patterning, and liver tissue interaction
(Springer Science and Business Media Deutschland GmbH, 2023)A precise nano-scale biosensor was developed here to detect Hg2+ in aqueous media. Nitrogen-doped carbon nanospheres (NCS) created from the pyrolysis of melamine–formaldehyde resin were characterized by FESEM, XRD, Raman ... -
Immunotherapeutic approaches in hepatocellular carcinoma: building blocks of hope in near future
(Elsevier, 2023)Hepatocellular carcinoma (HCC) is the most common type of primary hepatic cancer and is among the major causes of mortality due to cancer. Due to the lack of efficient conventional therapeutic options for this cancer, ... -
Hyperthermia of magnetically soft-soft core-shell ferrite nanoparticles
(MDPI, 2022)Magnetically soft-soft MnFe2O4-Fe3O4 core-shell nanoparticles were synthesized through a seed-mediated method using the organometallic decomposition of metal acetyl acetonates. Two sets of core-shell nanoparticles (S1 and ... -
Development of lateral flow assays for rapid detection of troponin ı: a review
(TAYLOR & FRANCIS INC, 2022)Troponin I as a particular and major biomarker of cardiac failure is released to blood demonstrating hurt of myocardial cells. Unfortunately, troponin I detection in the first hours of acute myocardial infarction usually ... -
Association of clinical features with spike glycoprotein mutations in Iranian COVID-19 patients
(MDPI, 2022)Background: Mutations in spike glycoprotein, a critical protein of SARS-CoV-2, could directly impact pathogenicity and virulence. The D614G mutation, a non-synonymous mutation at position 614 of the spike glycoprotein, is ... -
Antimicrobial activity of blow spun PLA/gelatin nanofibers containing green synthesized silver nanoparticles against wound ınfection-causing bacteria
(MDPI, 2022)One of the main challenges in wound healing is the wound infection due to various causes, of which moisture is the most important reason. Owing to this fact, wound dressings that can collect wound moisture in addition to ... -
Penicillin and oxacillin loaded on pegylated-graphene oxide to enhance the activity of the antibiotics against methicillin-resistant staphylococcus aureus
(MDPI, 2022)Infectious diseases are known as the second biggest cause of death worldwide, due to the development of antibiotic resistance. To overcome this problem, nanotechnology offers some promising approaches, such as drug delivery ... -
Synthesis and evaluation of novel xanthene-based thiazoles as potential antidiabetic agents
(WILEY-V C H VERLAG GMBH, 2022)A series of xanthene-based thiazoles was synthesized and characterized by different scpectroscopic methods, i.e. Proton nuclear magnetic resonance (H-1 NMR), carbon nuclear magnetic resonance (C-13 NMR), infrared spectroscopy, ... -
Soybean oil based allyl acrylates and methacrylates: synthesis, characterization, and polymerization
(WILEY-V C H VERLAG GMBH, 2022)In this study, a simple synthesis method for the allylic acrylates and methacrylates of soybean oil is evaluated. As a model compound, allylic acrylation and methacrylation of methyl oleate is also studied. IR and H-1 NMR ... -
Optimization of curcumin loaded niosomes for drug delivery applications
(Elsevier B.V., 2022)Controlled drug delivery is an important and challenging issue in pharmacology. The aim is to improve efficacy and reduce the side effects of drugs. Nanotechnology suggests applying various nanoparticles as carriers to ... -
Non-coding RNAs targeting notch signaling pathway in cancer : from proliferation to cancer therapy resistance
(Elsevier B.V., 2022)Cancer is a challenging to treat disease with a high mortality rate worldwide, nevertheless advances in science has led to a decrease in the number of death cases caused by cancer. Aberrant expression of genes occurs during ... -
Hybrid extracellular vesicles-liposome incorporated advanced bioink to deliver microRNA
(IOP Publishing, 2022)In additive manufacturing, bioink formulations govern strategies to engineer 3D living tissues that mimic the complex architectures and functions of native tissues for successful tissue regeneration. Conventional 3D-printed ... -
Stimuli-responsive liposomal nanoformulations in cancer therapy: Pre-clinical & clinical approaches
(Elsevier, 2022)The site-specific delivery of antitumor agents is of importance for providing effective cancer suppression. Poor bioavailability of anticancer compounds and the presence of biological barriers prevent their accumulation ... -
Customizing nano-chitosan for sustainable drug delivery
(PMC, 2022)Chitosan is a natural polymer with acceptable biocompatibility, biodegradability, and mechanical stability; hence, it has been widely appraised for drug and gene delivery applications. However, there has been no comprehensive ... -
Combination therapy using nanomaterials and stem cells to treat spinal cord injuries
(Elsevier Science, 2022)As a part of the central nervous system, the spinal cord (SC) provides most of the communications between the brain and other parts of the body. Any damage to SC interrupts this communication, leading to serious ... -
Molecular landscape of LncRNAs in prostate cancer: A focus on pathways and therapeutic targets for intervention
(PMC, 2022)Background: One of the most malignant tumors in men is prostate cancer that is still incurable due to its heterog‑ enous and progressive natures. Genetic and epigenetic changes play signifcant roles in its development. ... -
The apoptotic effect of ozone therapy on mitochondria of highly metastatic breast cancer cell line MDA-MB-231 using in vitro approaches
(KeAi, 2022)Ozone (O3) gas is the triatomic state of oxygen and it is used as a disinfection agent due to its strong oxidizing effect, since its discovery in the mid-nineteenth century. Ozone therapy is also an alternative therapeutic ... -
Non-coding RNA-based regulation of inflammation
(Elsevier Science, 2022)nflammation is a multifactorial process and various biological mechanisms and pathways participate in its development. The presence of inflammation is involved in pathogenesis of different diseases such as diabetes mellitus, ...