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Photodynamic therapy for leishmaniasis: recent advances and future trends

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Date

2021

Author

Varzandeh, Mohammad
Mohammadinejad, Reza
Esmaeilzadeh-Salestani, Keyvan
Dehshahri, Ali
Zarrabi, Ali
Aghaei-Afshar, Abbas

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Varzandeh, M., Mohammadinejad, R., Esmaeilzadeh-Salestani, K., Dehshahri, A., Zarrabi, A., & Aghaei-Afshar, A. (2021). Photodynamic therapy for leishmaniasis: recent advances and future trends. Photodiagnosis and photodynamic therapy, 102609. Advance online publication.

Abstract

Leishmaniasis has infected more than 12 million people worldwide. The neglected tropical disease causing 20,000-30,000 deaths per year determined as a global health problem. The emergence of resistant parasites and serious side effects of the conventional therapies has led to the search for less toxic and non-invasive alternative treatments. Photodynamic therapy is a promising therapeutic strategy to produce reactive oxygen species for the treatment of leishmaniasis. In this regard, natural and synthetic photosensitizers such as curcumin, hypericin, 5-aminolevulinic acid, phthalocyanines, phenothiazines, porphyrins, chlorins and nanoparticles have been applied. In this review, the recent advances on using photodynamic therapy for treating Leishmania species have been reviewed.

Source

Photodiagnosis Photodyn Ther.

Volume

36

URI

https://doi.org/10.1016/j.pdpdt.2021.102609
https://hdl.handle.net/20.500.12713/2232

Collections

  • Biyomedikal Mühendisliği Bölümü Makale Koleksiyonu [64]
  • PubMed İndeksli Yayınlar Koleksiyonu [1168]
  • Scopus İndeksli Yayınlar Koleksiyonu [1946]
  • WoS İndeksli Yayınlar Koleksiyonu [2067]



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