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dc.contributor.authorGürbüz, Defne
dc.contributor.authorKesimli, Mustafa Caner
dc.contributor.authorBilgili, Ahmet Mert
dc.contributor.authorDurmaz, Hacı Ömer
dc.date.accessioned2021-12-03T12:01:23Z
dc.date.available2021-12-03T12:01:23Z
dc.date.issued2021en_US
dc.identifier.citationGürbüz, D., Kesimli, M. C., Bilgili, A. M., & Durmaz, H. Ö. Evaluation of olfactory bulb volume in patients with diabetic olfactopathy and comparison with healthy individuals.en_US
dc.identifier.issn1781-782Xen_US
dc.identifier.urihttps://doi.org/10.5152/B-ENT.2021.21311
dc.identifier.urihttps://hdl.handle.net/20.500.12713/2300
dc.description.abstractObjective: Diabetic olfactopathy is defined as olfactory dysfunction in patients with diabetic neuropathy. In this study, we evaluated the olfactory bulb volume (OBV) using magnetic resonance imaging in patients with diabetic olfactopathy and compared the results with those of healthy individuals. Methods: This study included 12 patients who were diagnosed with type 2 diabetes mellitus (T2DM) and were found to have diabetic olfactopathy using the Connecticut Chemosensory Clinical Research Center (CCCRC) olfactory test (Group 1); their OBV was evaluated using MRI. For comparison, 13 healthy individuals of a similar age, without any medical problems, were included as a control group (Group 2); their OBV and olfactory functions were also evaluated. Results: Total CCCRC scores were 4.27 +/- 0.67 in Group 1 and 6.42 +/- 0.31 in Group 2; these scores significantly differed between the groups. The mean CCCRC scores in Groups 1 and 2 were moderately hyposmic and normosmic, respectively. The mean OBV values were 65.04 +/- 6.97 mm(3) and 76.46 +/- 11.36 mm(3) in Groups 1 and 2, respectively. Group 1 had significantly lower OBV values and CCCRC scores, compared with Group 2 (p < 0.01 for both groups). Conclusion: The OBV was lower in patients with T2DM who developed diabetic olfactopathy than that in healthy individuals; the olfactory bulb was adversely affected by diabetes mellitus. This is the first study to demonstrate that the olfactory bulb is adversely affected by the presence of diabetic olfactopathy.en_US
dc.language.isoenen_US
dc.publisherAVESen_US
dc.relation.ispartofB-ENTen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAnosmiaen_US
dc.subjectDiabetes Mellitusen_US
dc.subjectDiabethic Olfactopathyen_US
dc.subjectHyposmiaen_US
dc.subjectOlfactory Bulb Volumeen_US
dc.subjectSmell Disorderen_US
dc.titleEvaluation of olfactory bulb volume in patients with diabetic olfactopathy and comparison with healthy individualsen_US
dc.typeArticleen_US
dc.departmentİstinye Üniversitesi, Sağlık Hizmetleri Meslek Yüksekokulu, Ağız Ve Diş Sağlığı Bölümüen_US
dc.authoridMustafa Caner Kesimli / 0000-0003-1675-0394en_US
dc.institutionauthorKesimli, Mustafa Caner
dc.identifier.volume17en_US
dc.identifier.issue3en_US
dc.identifier.startpage174en_US
dc.identifier.endpage178en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.wosWOS:000723003900008en_US
dc.authorwosidMustafa Caner Kesimli / AAX-8405-2020
dc.authorscopusidMustafa Caner Kesimli / 56125668000
dc.identifier.scopus2-s2.0-85130150798en_US
dc.identifier.wosqualityQ4en_US
dc.identifier.doi10.5152/B-ENT.2021.21311en_US
dc.identifier.scopusqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US


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