Changes in HOMA-IR index levels after bariatric surgery: Comparison of single anastomosis duodenal switch-proximal approach (SADS-p) and one anastomosis gastric bypass-mini gastric bypass (OAGB-MGB)
MetadataShow full item record
CitationOzmen, M. M., Guldogan, C. E., & Gundogdu, E. (2020). Changes in HOMA-IR Index Levels After Bariatric Surgery: Comparison of Single Anastomosis Duodenal Switch-proximal approach (SADS-p) and One Anastomosis Gastric Bypass-Mini Gastric Bypass (OAGB-MGB). International Journal of Surgery.
Background: Bariatric surgery plays a major role in ameliorating metabolic abnormalities of type 2 diabetes (T2DM). The aim of this study was to evaluate the early effects of “Single Anastomosis Duodenal Switch-proximal approach” (SADS-p) and “One Anastomosis Gastric Bypass-Mini Gastric Bypass (OAGB-MGB) on the “homeostasis model assessment of insulin resistance” (HOMA-IR) index levels in morbidly obese patients with T2DM. Methods: In this retrospective 3-year trial, outcomes of SADS-p and OAGB-MGB patients were compared considering the changes in HOMA-IR index levels. All bariatric procedures were performed by a single primary surgeon recognized as a surgeon of excellence by IFSO-EC with the assistance of one or two additional attending surgeons. SADS-p was performed on 60(10 males) patients, and 200(27 males) patients underwent OAGB-MGB. Forty-six patients (78%) in the SADS-p group and 125 (63%) in the OAGB-MGB group had T2DM. Patients were evaluated before surgery and 1,3,9,12 months after surgery. Results: In both groups, the HOMA-IR index levels decreased significantly after surgery (p < 0.05), and both procedures markedly improved glycemic control. In the SADS-p group the HOMA-IR index levels significantly decreased from 6.2 to 1.4 after the 12th month of surgery (p < 0.05), in OAGB-MGB group HOMA-IR index levels significantly decreased from 5,9 to 1.7 after the 12th month of surgery (p < 0.05). Conclusion: Both procedures are promising operations which offer excellent control on weight, HOMA-IR index and diabetes. © 2020 IJS Publishing Group Ltd
SourceInternational Journal of Surgery
Showing items related by title, author, creator and subject.
Sumer, Aziz; Mahawar, Kamal; Vartanoglu Aktokmakyan, Talar; Savas, Osman Anıl; Peksen, Caghan; Barbaros, Umut; Mercan, Selcuk (Springer Link, 2021)Purpose: One-anastomosis gastric bypass (OAGB) is an established bariatric procedure performed worldwide. We developed a modification of OAGB leaving a bridge at the cranial 2 cm of the fundus as a gastro-gastric fistula ...
More and more people suffer from morbid obesity in the past several decades. Best treatment option for the obesity is still discussed. However, the accepted gold standard treatment for morbid obesity is bariatric surgery ...
Sumer, Aziz; Atasoy, Deniz; Barbaros, Umut; Savas, Osman Anil; Eren, Eryigit; Yurdaisik, Isil; Mercan, Selcuk (Mary Ann Liebert, Inc, 2019)Introduction: In this article, we aimed to report the first five cases of laparoscopic bridged mini gastric bypass (BMGB) in the treatment of obesity and type II diabetes mellitus (DM). Presentation of Cases: We have ...