Liver transplantation in hepatic myelopathy
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CitationAcar S, Dinckan A, Akyildiz M. Liver transplantation in hepatic myelopathy. Hepatol Forum. 2022 Apr 26;3(2):64-65. doi: 10.14744/hf.2021.2021.0004. PMID: 35783476; PMCID: PMC9243758.
Hepatic myelopathy (HMy) is a rare neurological complication of liver cirrhosis that involves spastic paraplegia caused by lateral cord demyelination especially due to the accumulation of some metabolites such as ammonia and manganese. We report a young adult woman presenting with spasticity and paraparesis in extremities after intrahepatic portosystemic shunting (TIPS) application and underwent deceased liver transplantation (LT). A 39-year-old woman underwent deceased LT because of cryptogenic liver cirrhosis. She underwent a TIPS procedure 5 years ago. After that, hepatic encephalopathy and spasticity appeared. She was on the waiting list for 3 years. Neurological findings after LT significantly decreased, but did not return to normal. After the emergence of neurological findings, the earlier LT can provide improvement in neurological findings.