Where cystatin C acts: inside or outside of the plaque
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CitationYetkin, E., Cuglan, B., Turhan, H., & Yalta, K. (2020). Where cystatin C acts: inside or outside of the plaque. Neurological Sciences, 1-2.
We have read the impressive article recently published by Ren et al. evaluating the plasma cystatin C (Cyst C) in patients with acute ischemic stroke (AIS) and carotid stenosis . Briefly, they have divided the patients into two groups based on their plasma Cyst C levels and assessed their relation with the degree of carotid stenosis, plaque burden, and morphology. The degree of atherosclerosis, the severity of plaques, and stenosis of the common carotid artery (CCA) of patients with AIS have been found to be significantly higher in the patients with high cystatin C levels. They have concluded that Cyst C levels are strongly correlated with symptomatic CCA stenosis and the rate of unstable plaques