Browsing PubMed İndeksli Yayınlar Koleksiyonu by Author "Zabolian, Amirhossein"
Now showing items 1-15 of 15
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Advances in understanding the role of P-gp in doxorubicin resistance: molecular pathways, therapeutic strategies, and prospects
Mirzaei, Sepideh; Gholami, Mohammad Hossein; Hashemi, Farid; Zabolian, Amirhossein; Zarrabi, Ali (Elsevier, 2022)P-glycoprotein (P-gp) is a drug efflux transporter that triggers doxorubicin (DOX) resistance. In this review, we highlight the molecular avenues regulating P-gp, such as Nrf2, HIF-1α, miRNAs, and long noncoding (lnc)RNAs, ... -
Cervical cancer progression is regulated by SOX transcription factors: Revealing signaling networks and therapeutic strategies
Paskeh, Mahshid Deldar Abad; Mirzaei, Sepideh; Gholami, Mohammad Hossein; Zarrabi, Ali; Zabolian, Amirhossein; Hashemi, Mehrdad; Hushmandi, Kiavash (Elsevier Science, 2021)Cervical cancer is the fourth common gynecologic cancer and is considered as second leading cause of death among women. Various strategies are applied in treatment of cervical cancer including radiotherapy, chemotherapy ... -
Correction: The long and short non-coding RNAs modulating EZH2 signaling in cancer (Journal of Hematology & Oncology, (2022), 15, 1, (18), 10.1186/s13045-022-01235-1)
Mirzaei, Sepideh; Gholami, Mohammad Hossein; Hushmandi, Kiavash; Hashemi, Farid; Zabolian, Amirhossein; Canadas, Israel; Zarrabi, Ali; Nabavi, Noushin; Aref, Amir Reza; Crea, Francesco; Wang, Yuzhuo; Ashrafizadeh, Milad; Kumar, Alan Prem (BioMed Central Ltd, 2022)The original article [1] contained an error in co-author, Farid Hashemi’s name which has since been corrected. © 2022, The Author(s). -
Curcumin and its derivatives in cancer therapy: potentiating antitumor activity of cisplatin and reducing side effects
Abadi, Asal Jalal; Mirzaei, Sepideh; Mahabady, Mahmood Khaksary; Hashemi, Farid; Zabolian, Amirhossein; Hashemi, Fardin; Raee, Pourya; Zarrabi, Ali (WILEY, 2021)Curcumin is a phytochemical isolated from Curcuma longa with potent tumor-suppressor activity, which has shown significant efficacy in pre-clinical and clinical studies. Curcumin stimulates cell death, triggers cycle arrest, ... -
Doxorubicin-loaded graphene oxide nanocomposites in cancer medicine: stimuli-responsive carriers, co-delivery and suppressing resistance
Ashrafizadeh, Milad; Saebfar, Hamidreza; Gholami, Mohammad Hossein; Hushmandi, Kiavash; Zabolian, Amirhossein; Zarrabi, Ali (2022)Introduction: The application of doxorubicin (DOX) in cancer therapy has been limited due to its drug resistance and poor internalization. Graphene oxide (GO) nanostructures have the capacity for DOX delivery while promoting ... -
Emerging role of exosomes in cancer progression and tumor microenvironment remodeling
Paskeh, Mahshid Deldar Abad; Entezari, Maliheh; Mirzaei, Sepideh; Zabolian, Amirhossein; Zarrabi, Ali (BioMed Central, 2022)Cancer is one of the leading causes of death worldwide, and the factors responsible for its progression need to be elucidated. Exosomes are structures with an average size of 100 nm that can transport proteins, lipids, and ... -
EZH2 as a new therapeutic target in brain tumors: Molecular landscape, therapeutic targeting and future prospects
Paskeh, Mahshid Deldar Abad; Mehrabi, Atefeh; Gholami, Mohammad Hossein; Zabolian, Amirhossein; Ranjbar, Ehsan; Zarrabi, Ali (Elsevier, 2022)Brain tumors are responsible for high mortality and morbidity worldwide. The brain tumor treatment depends on identification of molecular pathways involved in progression and malignancy. Enhancer of zeste homolog 2 (EZH2) ... -
The long and short non-coding RNAs modulating EZH2 signaling in cancer
Mirzaei, Sepideh; Gholami, Mohammad Hossein; Hushmandi, Kiavash; Hshemi, Farid; Zabolian, Amirhossein; Canadas, Israel; Zarrabi, Ali; Nabavi, Noushin; Aref, Amir Reza; Crea, Francesco; Wang, Yuzhuo; Ashrafizadeh, Milad; Kumar, Alan Prem (2022)Non-coding RNAs (ncRNAs) are a large family of RNA molecules with no capability in encoding proteins. However, they participate in developmental and biological processes and their abnormal expression affects cancer ... -
Long non-coding RNAs and exosomal incRNAs: Potential functions in lung cancer progression, drug resistance and tumor microenvironment remodeling
Entezari, Maliheh; Ghanbarirad, Maryam; Taheriazam, Afshin; Sadrkhanloo, Mehrdokht; Zabolian, Amirhossein; Shekhi Beig Goharrizi, Mohammad Ali; Hushmandi, Kiavash; Aref, Amir Reza; Ashrafizadeh, Milad; Zarrabi, Ali; Nabavi, Noushin; Rabiee, Navid; Hashemi, Mehrdad; Samarghandian, Saeed (Elsevier Science, 2022)Among the different kinds of tumors threatening human life, lung cancer is one that is commonly observed in both males and females. The aggressive behavior of lung cancer and interactions occurring in tumor microenvironment ... -
Long noncoding RNAs: A novel insight in the leukemogenesis and drug resistance in acute myeloid leukemia
Kirtonia, Anuradha; Ashrafizadeh, Milad; Hushmandi, Kiavash; Zabolian, Amirhossein; Bejandi, Atefe K.; Rani, Reshma; Pandey, Amit K.; Baligar, Prakash; Kumar, Vinit; Das, Bhudev C.; Garg, Manoj (Wiley-Blackwell, 2021)Acute myeloid leukemia (AML) is a common hematological disorder with heterogeneous nature that resulted from blocked myeloid differentiation and an enhanced number of immature myeloid progenitors. During several decades, ... -
Noncoding RNAs and their therapeutics in paclitaxel chemotherapy: Mechanisms of initiation, progression, and drug sensitivity
Mahabady, Mahmood K.; Mirzaei, Sepideh; Saebfar, Hamidreza; Gholami, Mohammad H.; Zabolian, Amirhossein; Hushmandi, Kiavash; Hashemi, Farid; Tajik, Fatemeh; Hashemi, Mehrdad; Kumar, Alan P.; Aref, Amir R.; Zarrabi, Ali; Khan, Haroon; Hamblin, Michael R.; Ertas, Yavuz Nuri; Samarghandian, Saeed (Wiley, 2022)The identification of agents that can reverse drug resistance in cancer chemotherapy, andenhance the overall efficacy is of great interest. Paclitaxel (PTX) belongs to taxane family hat exerts an antitumor effect by ... -
Resveratrol in breast cancer treatment: from cellular effects to molecular mechanisms of action
Behroozaghdam, Mitra; Dehghani, Maryam; Zabolian, Amirhossein; Kamali, Davood; Javanshir, Salar; Hasani Sadi, Farzaneh; Hashemi, Mehrdad; Tabari, Teimour; Rashidi, Mohsen; Mirzaei, Sepideh; Zarepour, Atefeh; Zarrabi, Ali; De Greef, Danielle; Bishayee, Anupam (Springer Science and Business Media Deutschland GmbH, 2022)Breast cancer (BC) is one of the most common cancers in females and is responsible for the highest cancer-related deaths following lung cancer. The complex tumor microenvironment and the aggressive behavior, heterogenous ... -
Targeted regulation of autophagy using nanoparticles: New insight into cancer therapy
Paskeh, Mahshid Deldar Abad; Entezari, Maliheh; Clark, Courtney; Zabolian, Amirhossein; Ranjbar, Ehsan; Zarrabi, Ali (Elsevier, 2022)Normal cells depend on autophagy to maintain cellular homeostasis by recycling damaged organelles and misfolded proteins and degrading toxic agents. Similar to apoptosis, targeting autophagy has been under attention in ... -
Targeting cancer stem cells by dietary agents: an important therapeutic strategy against human malignancies
Paskeh, Mahshid Deldar Abad; Asadi, Shafagh; Zabolian, Amirhossein; Saleki, Hossein; Khoshbakht, Mohammad Amin; Zarrabi, Ali (MDPI, 2021)As a multifactorial disease, treatment of cancer depends on understanding unique mechanisms involved in its progression. The cancer stem cells (CSCs) are responsible for tumor stemness and by enhancing colony formation, ... -
Targeting Nrf2 in ischemia-reperfusion alleviation: From signaling networks to therapeutic targeting
Sadrkhanloo, Mehrdokht; Entezari, Maliheh; Orouei, Sima; Zabolian, Amirhossein; Mirzaie, Amirreza; Maghsoudloo, Amin; Raesi, Rasoul; Asadi, Neda; Hashemi, Mehrdad; Zarrabi, Ali; Khan, Haroon; Mirzaei, Sepideh; Samarghandian, Saeed (Elsevier Inc., 2022)The nuclear factor erythroid 2-related factor 2 (Nrf2) is a master regulator of redox balance and it responds to various cell stresses that oxidative stress is the most well-known one. The Nrf2 should undergo nuclear ...
