Browsing PubMed İndeksli Yayınlar Koleksiyonu by Department "İstinye Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü"
Now showing items 1-18 of 18
-
Biomonitoring of heavy metal(oid)s in the residents of abandoned mining district in northern cyprus
(Springer, 2021)Abstract Several heavy metal(oid)s are known mutagens and/or carcinogens. Exposure to these elements can lead to the development of malignancies. Gemikonagi, which is in the western part of Cyprus, was the hometown of ... -
Challenge-comet assay, a functional and genomic biomarker for precision risk assessment and disease prevention among exposed workers
(Academic Press Inc Elsevier Science, 2020)Advancements in genomic technologies have ushered application of innovative changes into biomedical sciences and clinical medicine. Consequently, these changes have created enormous opportunities to implement precision ... -
Comparative Studies on Essential Oil and Phenolic Content with In Vitro Antioxidant, Anticholinesterase, Antimicrobial Activities of Achillea biebersteinii Afan. and A. millefolium subsp. millefolium Afan. L. Growing in Eastern Turkey
(2022)The potential applications of Achillea species in various industries have encouraged the examination of their phytochemical components along with their biological potential. In the present study, phenolic contents and ... -
Considerations into pharmacogenomics of COVID-19 pharmacotherapy: hope, hype and reality
(Academic Press, 2022)COVID-19 medicines, such as molnupiravir are beginning to emerge for public health and clinical practice. On the other hand, drugs display marked variability in their efficacy and safety. Hence, COVID-19 medicines, as with ... -
Cross referencing 2D-LC determination of intact gliptins in urine
(2020)Dipeptidyl peptidase-4 inhibitors, so-called gliptins, constitute a fairly novel class of oral hypoglycemic agents. The development and validation of an automated online SPE-LC-UV method to determine intact sitagliptin, ... -
Digging deeper into precision/personalized medicine: cracking the sugar code, the third alphabet of life, and sociomateriality of the cell
(Mary Ann Liebert, Inc, 2020)Precision/personalized medicine is a hot topic in health care. Often presented with the motto "the right drug, for the right patient, at the right dose, and the right time," precision medicine is a theory for rational ... -
Drug-associated cardiovascular risks: a retrospective evaluation of withdrawn drugs
(Kare Publ, 2019)A considerable number of drugs were withdrawn from the world market in the last decades due to safety reasons. A retrospective review of withdrawals is important in determining the adequacy of regulations regarding the ... -
The hCOMET project: international database comparison of results with the comet assay in human biomonitoring. baseline frequency of DNA damage and effect of main confounders
(Elsevier B.V., 2021)The alkaline comet assay, or single cell gel electrophoresis, is one of the most popular methods for assessing DNA damage in human population. One of the open issues concerning this assay is the identification of those ... -
How does infection with human papillomavirus 16 and 18 impact on dna damage and repair in cervical cells and peripheral blood?
(Mary Ann Liebert, Inc, 2018)Human papillomavirus (HPV) infection is one of the most common sexually transmitted diseases worldwide and a prime cause of cervical cancer. The HPV DNA is detected in approximately 80-90% of all cervical cancers, with HPV ... -
Insights into disease and pharmacotherapy knowledge of Alzheimer's disease among community pharmacists: a cross-sectional study
(TAYLOR & FRANCIS LTD, 2022)Objective To assess the knowledge level and awareness of Alzheimer's disease, including knowledge about the disease, pharmacotherapy, provision of patient education and associated factors among community pharmacists across ... -
It is time to revitalize the Antibiotic Pipeline: Systems ecology can help
(Mary Ann Liebert, Inc, 2020)Antimicrobials have been known for millennia, but innovative antibiotics are currently in short supply. New antimicrobial discoveries are being threatened by planetary scale loss of biodiversity that has important impacts ... -
The long view on COVID-19 theranostics and oral antivirals: living with endemic disease and lessons from molnupiravir
(Atypon, 2022)The long view on living with COVID-19 as an endemic disease calls for expanding the planetary health inter-vention toolbox. We will need a battery of vaccines, small molecule oral antiviral drugs, and biomarkers toforecast ... -
The potential chemo-preventive roles of Malus domestica against the risk of colorectal cancer: A suggestive insight into clinical application
(Elsevier Ltd, 2022)Biologically active compounds in fruit-derived ingredients, particularly phytochemicals, have significant potential to modulate and mitigate many pathological processes in the development of disease conditions, including ... -
Quinoline-based promising anticancer and antibacterial agents, and some metabolic enzyme inhibitors
(Wiley-VCH Verlag, 2020)A series of substituted quinolines was screened for their antiproliferative, cytotoxic, antibacterial activities, DNA/protein binding affinity, and anticholinergic properties by using the 3-(4,5-dimethylthiazol-2-yl)-2,5 ... -
Role of DNA repair genes XRCC3 and XRCC1 in predisposition to type 2 diabetes mellitus and diabetic nephropathy
(Elsevier Science Bv, 2019)Introduction: Increasing number of experimental and clinical studies suggest a strong relationship between hyperglycemia, oxidative stress, DNA damage and diabetic nephropathy (DN). Also, epidemiologic studies remark an ... -
Thanatechnology and the living dead: new concepts in digital transformation and human-computer interaction
(MARY ANN LIEBERT, 2021)In a digital society, shall we be the authors of our own experience, not only during our lifetime but also after we die? We ask this question because dying and bereavement have become even harder, and much less private, ... -
To genotype or phenotype for drug and food safety? Exiting the technology echo chambers
(Mary Ann Liebert, Inc, 2018)Scholars throughout history have argued there is nothing more important than understanding and explaining the world that we live in. Both scientists and social scientists share this motivation. Yet, they employ ... -
Voluntary oral methamphetamine increases memory deficits and contextual sensitization during abstinence associated with decreased PKMζ and increased κOR in the hippocampus of female mice
(Sage Journals, 2021)Background: Female populations exhibit vulnerabilities to psychostimulant addiction, as well as cognitive dysfunction following bouts of abuse. Aims: The goal for this study was to advance our understanding of the ...
