Browsing PubMed İndeksli Yayınlar Koleksiyonu by Department "İstinye Üniversitesi, Eczacılık Fakültesi, Eczacılık Temel Bilimleri Bölümü"
Now showing items 1-20 of 22
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Advancements and future directions in the antibacterial wound dressings - a review
(2021)Wound repair is a complex process that has not been entirely understood. It can conclude in several irregularities. Hence, designing an appropriate wound dressing that can accelerate the healing period is critical. Infections, ... -
Antivirals and the potential benefits of orally Inhaled Drug Administration in COVID-19 Treatment
(Elsevier Science, 2022)Coronavirus Disease 2019 (COVID-19) pandemic has been on the agenda of humanity for more than 2 years. In the meantime, the pandemic has caused economic shutdowns, halt of daily lives and global mobility, overcrowding ... -
Application of magnetic resonance imaging in liver biomechanics: a systematic review
(Frontiers, 2021)MRI-based biomechanical studies can provide a deep understanding of the mechanisms governing liver function, its mechanical performance but also liver diseases. In addition, comprehensive modeling of the liver can help ... -
Bioadhesive nanoparticles as potent drug delivery carriers
(Bentham Science Publishers, 2022)Background: Last years, nanotechnology-based systems have gained the interest of numerous scientists, especially for biomedical applications. Then, as called, nanocarriers present tunable abilities, can be easily functionalized ... -
Can lactate dehydrogenase inhibition be increased efficiency of 1,25(oh) 2 d 3 vitamin in prostate cancer animal model?
(Wiley, 2022)The Warburg effect explains that the cancer cell's metabolism is programmed based on anaerobic glycolysis to support the proliferation and anabolic growth of cancer cells. LDH-A is the form of LDH found in cancer cells, ... -
Combination of high performance liquid chromatography and flame atomic absorption spectrophotometry using a novel nebulizer interface supported T shaped slotted quartz tube for the determination of Vitamin B12
(Elsevier Science, 2022)A novel nebulizer interface (NI) was proposed to combine high performance liquid chromatography (HPLC) and flame atomic absorption spectrophotometer (FAAS). A glass concentric nebulizer was linked to T-shaped slotted quartz ... -
Crystal structure of bis(mesityl)(pyrrol-1-yl)borane
(Int Union Crystallography, 2022)In the crystal structure of the title compound, C22H26BN, the B atom acts to reduce the delocalization of the nitrogen lone-pair electron density into the pyrrole ring, so that the two N-C bonds increase in length to 1.4005 ... -
Current strategies and future perspectives of skin-on-a-chip platforms: innovations, technical challenges and commercial outlook
(Bentham Science Publ Ltd, 2018)The skin is the largest and most exposed organ in the human body. Not only it is involved in numerous biological processes essential for life but also it represents a significant endpoint for the application of pharmaceuticals. ... -
Current strategies for the regeneration of skeletal muscle tissue
(MDPI AG, 2021)Traumatic injuries, tumor resections, and degenerative diseases can damage skeletal muscle and lead to functional impairment and severe disability. Skeletal muscle regeneration is a complex process that depends on various ... -
Design of an amphiphilic hyperbranched core/shell-type polymeric nanocarrier platform for drug delivery
(TUBITAK, 2022)An amphiphilic core/shell-type polymer-based drug carrier system (HPAE- PCL-b-MPEG), composed of hyperbranched poly(aminoester)-based polymer (HPAE) as the core building block and poly(ethylene glycol)-bpoly(ε-caprolactone) ... -
Development and characterization of oxaceprol-loaded poly-lactide-co-glycolide nanoparticles for the treatment of osteoarthritis
(Wiley, 2020)Oxaceprol is well-defined therapeutic agent as an atypical inhibitor of inflammation in osteoarthritis. In the present study, we aimed to develop and characterize oxaceprol-loaded poly-lactide-co-glycolide (PLGA) nanoparticles ... -
Differential interactome proposes subtype-specific biomarkers and potential therapeutics in renal cell carcinomas
(MDPI, 2021)Abstract: Although many studies have been conducted on single gene therapies in cancer patients, the reality is that tumor arises from different coordinating protein groups. Unveiling perturbations in protein interactome ... -
Enzyme-mediated Alleviation of Peroxide Toxicity in Self-oxygenating Biomaterials
(2022)Oxygen releasing biomaterials can facilitate the survival of living implants by creating environments with a viable oxygen level. Hydrophobic oxygen generating microparticles (HOGMPs) encapsulated calcium peroxide (CPO) ... -
Layered double hydroxide-based nanocomposite scaffolds in tissue engineering applications
(Royal Society of Chemistry, 2021)Layered double hydroxides (LDHs), when incorporated into biomaterials, provide a tunable composition, controllable particle size, anion exchange capacity, pH-sensitive solubility, high-drug loading efficiency, efficient ... -
Magnetic Resonance Imaging-based biomechanical simulation of cartilage: a systematic review
(Elsevier, 2022)MRI-based mathematical and computational modeling studies can contribute to a better understanding of the mechanisms governing cartilage’s mechanical performance and cartilage disease. In addition, distinct modeling of ... -
Optimization of methacrylated gelatin /layered double hydroxides nanocomposite cell-laden hydrogel bioinks with high printability for 3D extrusion bioprinting
(John Wiley and Sons Inc, 2022)Layered double hydroxides (LDHs) offer unique source of inspiration for design of bone mimetic biomaterials due to their superior mechanical properties, drug delivery capability and regulation cellular behaviors, particularly ... -
Overview of omics biomarkers in pituitary neuroendocrine tumors to design future diagnosis and treatment strategies
(Springer Science and Business Media Deutschland GmbH, 2021)Pituitary neuroendocrine tumors (PitNETs) are the second most common type of intracranial neoplasia. Since their manifestation usually causes hormone hypersecretion, effective management of PitNETs is indisputably necessary. ... -
Photocurable silk fibroin-based tissue sealants with enhanced adhesive properties for the treatment of corneal perforations
(2022)Corneal defects are associated with corneal tissue engineering in terms of vision loss. The treatment of corneal defects is an important clinical challenge due to a uniform corneal thickness and the apparent lack of ... -
The repertoire of glycan alterations and glycoproteins in human cancers
(2021)Cancer as the leading cause of death worldwide has many issues that still need to be addressed. Since the alterations on the glycan compositions or/and structures (i.e., glycosylation, sialylation, and fucosylation) are ... -
Selective targeting of signet ring cell adenocarcinomas
(Churchill Livingstone, 2019)Many epithelial tumors, especially signet-ring cell adenocarcinomas, produce huge amounts of mucin glycoproteins that fill cytoplasm and push nucleus to the periphery, giving a signet ring like structure to the cell. Mucin ...
