PubMed İndeksli Yayınlar Koleksiyonu by Institution Author "Develi, Elif Sedef"

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Evidence for heterogeneity in response to treatment in mammary tumors of dogs as happens in humans

Turna, Ozge; Uvez, Ayca; Baykal, Aslihan; Develi, Elif Sedef; Diramali, Murat; Sonmez, Kivilcim; Karakas, Didem; Kasikci, Guven; Armutak, Elif Ilkay; Ulukaya, Engin (NCI CPTAC Assay Portal, 2022)

Tumors are formed by various clones developed over a long time. This gives rise to a heterogeneous nature. This heterogeneity is the hardest challenge in the treatment of cancers because it is the main reason for drug ...
Protoflavone-chalcone hybrids exhibit enhanced antitumor action through modulating redox balance, depolarizing the mitochondrial membrane, and inhibiting ATR-dependent signaling

Latif, Ahmed Dhahir; Jernei, Tamas; Podolski-Renic, Ana; Kuo, Ching-Ying; Vagvolgyi, Mate; Girst, Gabor; Zupko, Istvan; Develi, Elif Sedef; Ulukaya, Engin; Wang, Hui-Chun; Pesic, Milica; Csampai, Antal; Hunyadi, Attila (Mdpi, 2020)

Hybrid compounds combine fragments with complementary targets to achieve a common pharmacological goal. This approach represents an increasingly popular strategy for drug discovery. In this work, we aimed to design antitumor ...