ASSOCIATION BETWEEN HLA CLASS II ALLELES AND MORBID OBESITY Basic science and research in bariatric surgery
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CitationOzmen, F., Ergen, G. O., Sahin, T. T., & Ozmen, M. M. (2019). ASSOCIATION BETWEEN HLA CLASS II ALLELES AND MORBID OBESITY Basic science and research in bariatric surgery. OBESITY SURGERY, 29(5), 184.
Background and Aims: Morbid obesity is a multifactorial disease. Adiposity hypertrophia and activation of immune cells play very important roles in obesity pathogenesis. Human Leukocyte Antigen (HLA) class II HLA-DR and HLA-DQ loci are also related to some inflammatory and autoimmune diseases. The present study aims to analyze the association of HLA-DRB1 and HLA-DQB1 alleles with morbid obesity disease.