Disseminated fungal infection by Aureobasidium pullulans in a renal transplant recipient
Yakupoglu, Y. Kamil
Sensoy, Sema Gulnar
MetadataShow full item record
CitationNalcacioglu, H., Yakupoglu, Y. K., Genc, G., Belet, N., Sensoy, S. G., Birinci, A., & Ozkaya, O. (2018). Disseminated fungal infection by Aureobasidium pullulans in a renal transplant recipient. Pediatric Transplantation, 22(3), e13152.
Renal transplant recipients are on long-term potent immunosuppressive therapy, which makes them highly vulnerable to opportunistic fungal infections. Dematiaceous, or dark-pigmented saprophytic fungi, are being increasingly seen as opportunistic pathogens of mycoses in immunosuppressed patients. One of these is Aureobasidium pullulans, which is a black yeast-like dematiaceous fungus found ubiquitously in the environment that can cause various opportunistic human infections. Most infections occur by traumatic inoculation, such as keratitis and cutaneous lesions; disseminated mycoses are very rare and occur only in severely immunocompromised patients. We report a case of disseminated fungal infection due to A.pullulans in a pediatric patient who underwent renal transplant. The use of voriconazole and vacuum-assisted closure along with surgical drainage most likely contributed to the patient's positive outcome.