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dc.contributor.authorTerzioglu, Fusun
dc.contributor.authorKarahalil, Bensu
dc.contributor.authorYucel, Cigdem
dc.contributor.authorTurk, Rukiye
dc.date.accessioned2020-08-30T20:08:24Z
dc.date.available2020-08-30T20:08:24Z
dc.date.issued2016
dc.identifier.citationTERZİOĞLU, F., Karahalil, B., YÜCEL, Ç., & Türk, R. (2016). The effect of cotinine concentrations in seminal plasma and follicular fluid on the pregnancy outcomes of couples undergoing assisted reproductive techniques. Turkish journal of medical sciences, 46(5), 1495-1501.en_US
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.urihttps://doi.org/10.3906/sag-1504-121
dc.identifier.urihttps://hdl.handle.net/20.500.12713/932
dc.descriptionWOS: 000389053000034en_US
dc.descriptionPubMed: 27966320en_US
dc.description.abstractBackground/aim:This study determined the effects of cotinine concentrations in follicular fluid (FF) and seminal plasma (SP) on the pregnancy outcome of couples using assisted reproductive techniques (ARTs). Materials and methods: This study was conducted as a case-control study. A total of 217 couples were included in the study. Among these couples, there were nonsmokers (66 women and 40 men), passive smokers (106 women and 54 men), and active smokers (45 women and 123 men). Demographic and smoking data were collected by questionnaire at the onset of treatment. FF and SP samples were obtained from the couples on the day of oocyte retrieval. Results: The cotinine concentrations in the FF and SP of nonsmokers were significantly lower than they were in the other groups (P = 0.001). The difference in cotinine concentrations detected in FF between women with positive pregnancy test results and women with negative pregnancy test results was statistically insignificant. It was also determined that the percentage of clinical pregnancy was lower in nonsmoker women than in passive smoker or smoker women (P > 0.05). Conclusion: Although we found there was no significant difference in the pregnancy outcome between nonsmoker and passive smoker or smoker women, smoking cessation should be an integral part of ARTs.en_US
dc.description.sponsorshipHacettepe University Scientific Research Projects Coordination UnitHacettepe University [0801401001(913)]en_US
dc.description.sponsorshipThe authors thank the couples that participated in the study. The authors also thank Dr Ozgur Cinar and Dr Serdar Dilbaz for collecting and preparing the follicular fluid and seminal plasma samples. This study is a project funded by the Hacettepe University Scientific Research Projects Coordination Unit (Project No: 0801401001(913)). A part of this study was presented at the 14th World Congress on Controversies in Obstetrics, Gynecology & Infertility, 17-20 November 2011, Paris, France. There is another publication generated from this project. The paper, entitled "Does cigarette smoking really have detrimental effects on outcomes of IVF?" is published in the European Journal of Obstetrics & Gynecology and Reproductive Biology (Eur J Obstet Gynecol Reprod Biol 2014, 174, 106-110).en_US
dc.language.isoengen_US
dc.publisherTubitak Scientific & Technical Research Council Turkeyen_US
dc.relation.isversionof10.3906/sag-1504-121en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectInfertilityen_US
dc.subjectAssisted Reproductive Techniquesen_US
dc.subjectSeminal Plasmaen_US
dc.subjectFollicular Fluiden_US
dc.subjectCigaretteen_US
dc.subjectCotinine Concentrationsen_US
dc.titleThe effect of cotinine concentrations in seminal plasma and follicular fluid on the pregnancy outcomes of couples undergoing assisted reproductive techniquesen_US
dc.typearticleen_US
dc.contributor.departmentİstinye Üniversitesi, Sağlık Bilimleri Fakültesi, Hemşirelik Bölümüen_US
dc.contributor.institutionauthorTerzioglu, Fusunen_US
dc.identifier.volume46en_US
dc.identifier.issue5en_US
dc.identifier.startpage1495en_US
dc.identifier.endpage1501en_US
dc.relation.journalTurkish Journal of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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